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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Int J Public Health</journal-id>
<journal-title>International Journal of Public Health</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Int J Public Health</abbrev-journal-title>
<issn pub-type="epub">1661-8564</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">1604401</article-id>
<article-id pub-id-type="doi">10.3389/ijph.2022.1604401</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Public Health Archive</subject>
<subj-group>
<subject>Original Article</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Social Support and Depressive Symptoms in the Context of COVID-19 Lockdown: The Moderating Role of Attachment Styles</article-title>
<alt-title alt-title-type="left-running-head">Costa-Cordella et al.</alt-title>
<alt-title alt-title-type="right-running-head">Attachment, Social Support and Depression</alt-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<name>
<surname>Costa-Cordella</surname>
<given-names>Stefanella</given-names>
</name>
<xref ref-type="aff" rid="aff1">
<sup>1</sup>
</xref>
<xref ref-type="aff" rid="aff2">
<sup>2</sup>
</xref>
<xref ref-type="aff" rid="aff3">
<sup>3</sup>
</xref>
<xref ref-type="corresp" rid="c001">&#x2a;</xref>
<uri xlink:href="https://loop.frontiersin.org/people/1450689/overview"/>
</contrib>
<contrib contrib-type="author" corresp="yes">
<name>
<surname>Vivanco-Carlevari</surname>
<given-names>Anastassia</given-names>
</name>
<xref ref-type="aff" rid="aff4">
<sup>4</sup>
</xref>
<xref ref-type="aff" rid="aff5">
<sup>5</sup>
</xref>
<xref ref-type="corresp" rid="c001">&#x2a;</xref>
<uri xlink:href="https://loop.frontiersin.org/people/425009/overview"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Rossi</surname>
<given-names>Alejandra</given-names>
</name>
<xref ref-type="aff" rid="aff2">
<sup>2</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Ar&#xe9;valo-Romero</surname>
<given-names>Camilo</given-names>
</name>
<xref ref-type="aff" rid="aff2">
<sup>2</sup>
</xref>
<xref ref-type="aff" rid="aff6">
<sup>6</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Silva</surname>
<given-names>Jaime R.</given-names>
</name>
<xref ref-type="aff" rid="aff3">
<sup>3</sup>
</xref>
<xref ref-type="aff" rid="aff4">
<sup>4</sup>
</xref>
<xref ref-type="aff" rid="aff7">
<sup>7</sup>
</xref>
<uri xlink:href="https://loop.frontiersin.org/people/205393/overview"/>
</contrib>
</contrib-group>
<aff id="aff1">
<sup>1</sup>
<institution>Centro de Estudios en Psicolog&#xed;a Cl&#xed;nica y Psicoterapia</institution>, <institution>Facultad de Psicolog&#xed;a</institution>, <institution>Universidad Diego Portales</institution>, <addr-line>Santiago</addr-line>, <country>Chile</country>
</aff>
<aff id="aff2">
<sup>2</sup>
<institution>Centro de Estudios en Neurociencia y Neuropsicolog&#xed;a Humana</institution>, <institution>Facultad de Psicolog&#xed;a</institution>, <institution>Universidad Diego Portales</institution>, <addr-line>Santiago</addr-line>, <country>Chile</country>
</aff>
<aff id="aff3">
<sup>3</sup>
<institution>Millennium Institute for Depression and Personality Research (MIDAP)</institution>, <addr-line>Santiago</addr-line>, <country>Chile</country>
</aff>
<aff id="aff4">
<sup>4</sup>
<institution>Facultad de Psicolog&#xed;a</institution>, <institution>Universidad de Desarrollo</institution>, <addr-line>Santiago</addr-line>, <country>Chile</country>
</aff>
<aff id="aff5">
<sup>5</sup>
<institution>Department of Psychology</institution>, <institution>Faculty of Social and Behavioural Sciences</institution>, <institution>University of Amsterdam</institution>, <addr-line>Amsterdam</addr-line>, <country>Netherlands</country>
</aff>
<aff id="aff6">
<sup>6</sup>
<institution>Mag&#xed;ster en Neurociencia Social</institution>, <institution>Facultad de Psicolog&#xed;a</institution>, <institution>Universidad Diego Portales</institution>, <addr-line>Santiago</addr-line>, <country>Chile</country>
</aff>
<aff id="aff7">
<sup>7</sup>
<institution>Clinica Alemana de Santiago</institution>, <addr-line>Santiago</addr-line>, <country>Chile</country>
</aff>
<author-notes>
<fn fn-type="edited-by">
<p>
<bold>Edited by:</bold> <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/293949/overview">Jutta Linder</ext-link>, University of Applied Sciences Emden Leer, Germany</p>
</fn>
<fn fn-type="edited-by">
<p>
<bold>Reviewed by:</bold> <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/1606258/overview">&#x391;reti Spyropoulou</ext-link>, National and Kapodistrian University of Athens, Greece</p>
<p>
<ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/1697795/overview">Ruth Sharabany</ext-link>, University of Haifa, Israel</p>
</fn>
<corresp id="c001">&#x2a;Correspondence: Stefanella Costa-Cordella, <email>stefanella.costa@mail.udp.cl</email>; Anastassia Vivanco-Carlevari, <email>avivanco@udd.cl</email>
</corresp>
<fn fn-type="other" id="fn001">
<p>This Original Article is part of the IJPH Special Issue &#x201c;The Impact of the COVID-19 Pandemic on Mental Health.&#x201d;</p>
</fn>
</author-notes>
<pub-date pub-type="epub">
<day>15</day>
<month>06</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="collection">
<year>2022</year>
</pub-date>
<volume>67</volume>
<elocation-id>1604401</elocation-id>
<history>
<date date-type="received">
<day>11</day>
<month>08</month>
<year>2021</year>
</date>
<date date-type="accepted">
<day>20</day>
<month>05</month>
<year>2022</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#xa9; 2022 Costa-Cordella, Vivanco-Carlevari, Rossi, Ar&#xe9;valo-Romero and Silva.</copyright-statement>
<copyright-year>2022</copyright-year>
<copyright-holder>Costa-Cordella, Vivanco-Carlevari, Rossi, Ar&#xe9;valo-Romero and Silva</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p>
</license>
</permissions>
<abstract>
<p>
<bold>Objectives:</bold> COVID-19 sanitary measures (social distancing, school closures) have deeply impacted social life, support networks, and their protective role in mental health. The present study aims to understand how attachment styles influence the way individuals experience social support. Particularly, investigating its moderating role in the relationship between social support and depression.</p>
<p>
<bold>Methods:</bold> An online survey was designed to clarify the role of adult attachment styles (ECR-S) in the perceived social support (MOSS) and self-reported depressive symptoms (BDI-SF) in the COVID-19 context.</p>
<p>
<bold>Results:</bold> Positive social interactions was the most important dimension of social support for lower depression symptoms. Individuals attachment strategies have a moderating role in the relation between of social support and depression. Crucially, insecure attachment style wanes the positive impact of social support in depression.</p>
<p>
<bold>Conclusion:</bold> Aligned with the existing literature, attachment security is an essential factor in our current understanding of relationships and mental health. Exploring specific and indivual attachment strategies might be a powerful tool to protect population&#x2019;s mental healt.</p>
</abstract>
<kwd-group>
<kwd>mental health</kwd>
<kwd>COVID-19</kwd>
<kwd>depression</kwd>
<kwd>social support</kwd>
<kwd>attachment</kwd>
<kwd>attachment theory</kwd>
</kwd-group>
</article-meta>
</front>
<body>
<sec id="s1">
<title>Introduction</title>
<p>Humans are primarily dependent on others for survival. This necessity underpins a set of behaviours to reach proximity with significant others (i.e., attachment strategies, [<xref ref-type="bibr" rid="B1">1</xref>]). The way in which our early social environment answered our needs is thought to be related to how we look for help later in our life, as well as how helpful we experience other&#x2019;s support to be [<xref ref-type="bibr" rid="B2">2</xref>, <xref ref-type="bibr" rid="B3">3</xref>]. These patterns would shape the social world in which our mental health is rooted [<xref ref-type="bibr" rid="B4">4</xref>&#x2013;<xref ref-type="bibr" rid="B6">6</xref>].</p>
<p>From a health science perspective the resources that flow through and from social relationships are known as social support: the available support for individuals through social ties with other people, groups, or the community in general [<xref ref-type="bibr" rid="B7">7</xref>, <xref ref-type="bibr" rid="B8">8</xref>].</p>
<p>Research and practice on mental health have been increasingly interested in social support, as it promotes mental well-being [<xref ref-type="bibr" rid="B9">9</xref>&#x2013;<xref ref-type="bibr" rid="B11">11</xref>] and decreases the risk for psychopathology [<xref ref-type="bibr" rid="B4">4</xref>, <xref ref-type="bibr" rid="B12">12</xref>], especially depression [<xref ref-type="bibr" rid="B13">13</xref>&#x2013;<xref ref-type="bibr" rid="B19">19</xref>]. Perceiving ourselves as socially connected with others can prevent depression even in the presence of other known risk factors (e.g., early trauma) [<xref ref-type="bibr" rid="B13">13</xref>, <xref ref-type="bibr" rid="B14">14</xref>, <xref ref-type="bibr" rid="B16">16</xref>]. Also, people with depression who present high levels of social support show a better prognosis [<xref ref-type="bibr" rid="B17">17</xref>, <xref ref-type="bibr" rid="B18">18</xref>] and higher quality of life during the course and treatment of the disorder [<xref ref-type="bibr" rid="B19">19</xref>].</p>
<p>However, the positive effect of social support on mental health varies significantly among different people [<xref ref-type="bibr" rid="B20">20</xref>, <xref ref-type="bibr" rid="B21">21</xref>]. Perceiving interactions as supportive (i.e., perceived social support) have a stronger effect on mental health outcomes than objective features of social support such as network size, frequency of contact with significant others, or material support (i.e., received support) [<xref ref-type="bibr" rid="B20">20</xref>, <xref ref-type="bibr" rid="B22">22</xref>, <xref ref-type="bibr" rid="B23">23</xref>].</p>
<p>In this context, attachment theory provides a productive approach to understand the variability in the effect of social support; specifically, the way different attachment styles shape both the perception and the experience of social support [<xref ref-type="bibr" rid="B3">3</xref>, <xref ref-type="bibr" rid="B24">24</xref>, <xref ref-type="bibr" rid="B25">25</xref>].</p>
<sec id="s1-1">
<title>Attachment Theory</title>
<p>Attachment theory posits that human beings are born with a psychobiological system -the attachment system- whose main role is to regulate stress and interpersonal relationships across the lifespan [<xref ref-type="bibr" rid="B1">1</xref>, <xref ref-type="bibr" rid="B2">2</xref>].</p>
<p>In children, the experience of stress activates the attachment system, motivating the child&#xb4;s proximity-seeking behaviours (e.g., crying) to significant others (attachment figures). From the caregiver&#xb4;s point of view, this request activates her caregiving system: a set of behaviours to regulate the child&#x2019;s distress [<xref ref-type="bibr" rid="B26">26</xref>].</p>
<p>The repetition of these interactions generates a system of social expectations in children: an &#x201c;internal model&#x201d; [<xref ref-type="bibr" rid="B27">27</xref>] of how relationships work. This model set the basis for a pattern of attachment strategies, also called attachment styles in adulthood [<xref ref-type="bibr" rid="B27">27</xref>]. According to longitudinal studies [<xref ref-type="bibr" rid="B28">28</xref>, <xref ref-type="bibr" rid="B29">29</xref>], attachment has a fundamental role during the whole lifespan and can be measured throughout life with a 69%&#x2013;75% concordance between attachment styles during childhood to adulthood.</p>
<p>Four attachment styles have been identified: secure, insecure-avoidant, insecure-anxious, and disorganised [<xref ref-type="bibr" rid="B29">29</xref>]. In short, people with secure attachment can show signs of their distress and look for help, expecting that others will be available to help and be actually helpful. Avoidant attachment styles are characterised by hidden distress, even when physiological signs of stress are present [<xref ref-type="bibr" rid="B30">30</xref>]. People with avoidant attachment style tend to be emotionally overregulated: visible stress signals are suppressed to keep the closeness with the attachment figure. This behaviour is believed to be rooted in fear of others&#x2019; rejection in front of negative emotion [<xref ref-type="bibr" rid="B2">2</xref>]. Attachment avoidance implies efforts to maintain distance from others, expressed in compulsive self-reliance and omission of help-seeking in front of stressful situations [<xref ref-type="bibr" rid="B2">2</xref>].</p>
<p>In contrast, anxious attachment is expressed in an intense need to be close to attachment figures, high anxiety levels upon separation, and a general emotional under-regulation. It is also characterised by an exaggerated expression of distress, excessive pursuit of other&#x2019;s care, and a constant preoccupation that others will not be available when needed [<xref ref-type="bibr" rid="B2">2</xref>].</p>
<p>Lastly, people with disorganised attachment orientation show an inconsistent pattern of attachment activation-deactivation as a product of repeated experiences with threatening caregiving figures [<xref ref-type="bibr" rid="B29">29</xref>].</p>
<p>Hence, different attachment styles can potentially shape the experience of interpersonal relationships. Then, it becomes relevant to ask about the role different attachment styles have in the perception of social support as explained below.</p>
</sec>
<sec id="s1-2">
<title>Attachment, Social Support, and Depression in the COVID-19 Context</title>
<p>The effect of attachment styles on perceived social support has been extensively studied [<xref ref-type="bibr" rid="B31">31</xref>&#x2013;<xref ref-type="bibr" rid="B33">33</xref>]. Securely attached individuals perceive their relationships as more supportive and are generally more satisfied with the received support [<xref ref-type="bibr" rid="B32">32</xref>, <xref ref-type="bibr" rid="B33">33</xref>]. By contrast, non-securely attached individuals report low availability of supportive figures and less satisfaction in social interactions [<xref ref-type="bibr" rid="B24">24</xref>, <xref ref-type="bibr" rid="B34">34</xref>]. Specifically, people showing anxious attachment styles tend to initially idealise supportive figures, but they become easily disappointed, remaining with feelings of hopelessness [<xref ref-type="bibr" rid="B31">31</xref>, <xref ref-type="bibr" rid="B35">35</xref>]. In opposition, avoidant attachment has been related to feelings of discomfort when depending on others for support, suppressing the expression of distress, and support-seeking behaviours [<xref ref-type="bibr" rid="B31">31</xref>]. In conclusion, attachment styles influence the way individuals experience social support.</p>
<p>As previously mentioned, the positive effect of social support on mental health is well documented but the characteristics of the individual differences in this relationship are still unexplored. It is relevant to understand these differences to progress in the study and treatment of mental health disorders, particularly in mood disorders like depression. Depression and depressive symptoms have been established as one of the main priorities in health research [<xref ref-type="bibr" rid="B36">36</xref>] due to its high and increasing prevalence and long-term consequences [<xref ref-type="bibr" rid="B37">37</xref>].</p>
<p>In the present context of the COVID-19 pandemic, depression has become of the greatest public health concern as its incidence has dramatically risen [<xref ref-type="bibr" rid="B38">38</xref>, <xref ref-type="bibr" rid="B39">39</xref>]. The deep changes in daily social dynamics imposed by the pandemic are one of the contextual aspects of this increment [<xref ref-type="bibr" rid="B39">39</xref>, <xref ref-type="bibr" rid="B40">40</xref>]. In this context, the role of attachment in the relationship between social support and depression becomes exceptionally relevant. Particularly, since the current COVID-19 pandemic is a known factor of stress [<xref ref-type="bibr" rid="B39">39</xref>, <xref ref-type="bibr" rid="B41">41</xref>, <xref ref-type="bibr" rid="B42">42</xref>]. As such, the pandemic has the potential to activate the attachment system [<xref ref-type="bibr" rid="B43">43</xref>]. In <xref ref-type="fig" rid="F1">Figure 1</xref>, we offer a model for understanding the plausible effect of COVID-19 pandemic on attachment, social support, and the link with mental health outcomes such as depressive symptoms.</p>
<fig id="F1" position="float">
<label>FIGURE 1</label>
<caption>
<p>Model possible effects of the COVID-19 pandemic on attachment, social support and its relationship with mental health. Chile, 2021.</p>
</caption>
<graphic xlink:href="ijph-67-1604401-g001.tif"/>
</fig>
<p>In insecurely attached individuals, the stress activation may result in either a hyperactivation of the attachment system (anxious attachment style) and excessive dependence on others or deactivation of the attachment system (avoidant attachment style) and compulsive self-reliance. In both cases, as discussed above, the experience of support from others would be negatively altered.</p>
<p>In a secure attachment, the activation of the attachment system and the consequent help-seeking behaviours can help look for social contact and positively use those social interactions. However, the range of measures to protect public health includes social distancing and social isolation as key prevention of COVID-19 incidence. In this context, even securely attached people who could benefit from social support in normal conditions cannot rely on their usual stress regulation strategies. Thus, the usual strategies to deal with stress are unavailable, leading the stress systems to continue to be activated.</p>
<p>In this scenario, secure attachment strategies are not necessarily helpful, and therefore insecure attachment strategies may get activated, which, in turn, impede the perception of social support. This process has the potential to affect mental health negatively.</p>
</sec>
<sec id="s1-3">
<title>The Present Study</title>
<p>Although there is growing evidence for the role of social support and attachment in mental health [<xref ref-type="bibr" rid="B25">25</xref>, <xref ref-type="bibr" rid="B44">44</xref>&#x2013;<xref ref-type="bibr" rid="B46">46</xref>], and particularly in depression [<xref ref-type="bibr" rid="B46">46</xref>, <xref ref-type="bibr" rid="B47">47</xref>], no study to date has investigated the moderating role of attachment in the relationship between social support and depression in the context of COVID-19 pandemic. Reports show that the pandemic sanitary procedures (e.g., social distancing, repeated lockdowns, school closures) and the fear of contracting the virus among other precautionary measures have heavily impacted mental health [<xref ref-type="bibr" rid="B39">39</xref>, <xref ref-type="bibr" rid="B48">48</xref>, <xref ref-type="bibr" rid="B49">49</xref>].</p>
<p>Chilean circumstances have been particularly challenging. First, the pandemic started above a disrupted social context due to the 2019 social outbreak that has had important social, political and economic consequences [<xref ref-type="bibr" rid="B50">50</xref>], which are known risk factors for mental health [<xref ref-type="bibr" rid="B51">51</xref>]. Second, since mid-March 2020 Chile adopted severe restrictions on movement and social contact [<xref ref-type="bibr" rid="B52">52</xref>] with already known negative consequences on people&#x2019;s mental health [<xref ref-type="bibr" rid="B53">53</xref>]. Third, because of both sanitary and social crisis, a large percentage of the population has faced serious economic difficulties [<xref ref-type="bibr" rid="B52">52</xref>].</p>
<p>Therefore, the present study aims to explore the predictive role of social support on depressive symptoms and the moderating role of attachment styles in the association between social support and depressive symptomatology.</p>
<p>Based on the previous literature [<xref ref-type="bibr" rid="B3">3</xref>, <xref ref-type="bibr" rid="B25">25</xref>, <xref ref-type="bibr" rid="B44">44</xref>, <xref ref-type="bibr" rid="B47">47</xref>, <xref ref-type="bibr" rid="B54">54</xref>], we hypothesised that securely attached individuals are more likely to display support seeking behaviours and that these strategies will positively influence their mental health. In contrast, insecurely attached individuals (either anxious or avoidant) under stress tend to isolate and behave in a compulsively self-reliant way; therefore, they will not look for help from others, impeding the benefit from social support.</p>
<p>Based on the evidence mentioned above, we expect to find 1) higher perceived social support to be associated with lower depressive symptoms; 2) higher attachment security to be associated with lower depressive symptoms, and 3) a moderating role of attachment in the association between social support and depressive symptomatology.</p>
</sec>
</sec>
<sec sec-type="methods" id="s2">
<title>Methods</title>
<sec id="s2-1">
<title>Participants and Procedure</title>
<p>One hundred and eighty-eight participants answered the set of online questionnaires and were included in the study analyses (N women &#x3d; 148) during December 2020 and January 2021 (i.e., after 9&#xa0;months of severe restrictions to social contact and during one of the strict lockdown periods). Five participants left an item blank on one of the self-reported scales. These missing values were substituted by the mean series method, using the mean of the values answered by the participant on the same scale. The sample&#x2019;s mean age was 39.78 (<italic>SD</italic> &#x3d; 14.72), ranging between 18 and 80&#xa0;years old. 87.7% of participants reported having completed undergraduate or postgraduate education. Analysis related to sociodemographic information and the study variables is available in the <xref ref-type="sec" rid="s9">Supplementary File S1</xref>.</p>
<p>Participants were invited to voluntarily join the study through different online platforms. All participants agreed through informed consent, which was approved on 12/29/2020 by the Ethics Committee of Universidad del Desarrollo. As retribution for participating, three gift cards valued at $100.000 CLP (around $120 US) were raffled at the end of the data collection.</p>
<p>The sample size was previously calculated through power analysis using the G&#x2a;Power program. Anticipating an effect size of 0.15, <italic>p</italic>-value &#x3e; 0.05 and <italic>B</italic> &#x3d; 0.95, the minimum sample size required was N &#x3d; 129. Questionnaires were displayed on the Survey monkey online platform (<ext-link ext-link-type="uri" xlink:href="https://es.surveymonkey.com/">https://es.surveymonkey.com/</ext-link>). The whole survey took approximately 10&#x2013;15&#xa0;min for participants to complete. Only participants with completed surveys were considered as part of this study.</p>
</sec>
<sec id="s2-2">
<title>Instruments</title>
<p>Participants were asked to complete the following three scales. Further details of these instruments and data analysis plan are available in the <xref ref-type="sec" rid="s9">Supplementary File S1</xref>.</p>
<p>The Medical Outcome Study Social Support Survey (MOSS; [<xref ref-type="bibr" rid="B55">55</xref>]) measures perceived social support and it is validated for the Chilean population [<xref ref-type="bibr" rid="B56">56</xref>]. This 18 items instrument uses a 5-point Likert scale (from 1 &#x3d; Never; to 5 &#x3d; Always) and an additional item assessing social network size. MOSS includes five dimensions: positive social interactions, affectionate support, instrumental support, emotional/informational support, and the social network size.</p>
<p>The Experiences in Close Relationship Scale Short Form [<xref ref-type="bibr" rid="B57">57</xref>] was adapted to measure adult attachment in general relationships (Adaptation process in <xref ref-type="sec" rid="s9">Supplementary File S2</xref>). The modified version of the ECR-S used in this study has 12 items with seven response levels (from 1 &#x3d; strongly disagreer; to 7 &#x3d; strongly agree). The instrument allows to obtain an index of anxious and avoidant attachment for respondents.</p>
<p>The Beck Depression Inventory-Short Form (BDI-SF; [<xref ref-type="bibr" rid="B58">58</xref>]) measures depressive symptoms. We used the version validated for the Chilean population [<xref ref-type="bibr" rid="B59">59</xref>], and shows good reliability and validity in various populations [<xref ref-type="bibr" rid="B58">58</xref>, <xref ref-type="bibr" rid="B59">59</xref>].</p>
</sec>
</sec>
<sec sec-type="results" id="s3">
<title>Results</title>
<sec id="s3-1">
<title>Association Between Social Support and Depressive Symptoms</title>
<p>The linear regression analysis evidenced a significant negative association between social support and reported depressive symptoms (<italic>F</italic>(1,186) &#x3d; 33.971, <italic>p</italic> &#x3c; 0.001) with a <inline-formula id="inf1">
<mml:math id="m1">
<mml:mrow>
<mml:msup>
<mml:mi>R</mml:mi>
<mml:mn>2</mml:mn>
</mml:msup>
</mml:mrow>
</mml:math>
</inline-formula> &#x3d; 0.154. Specifically, for each increasing point of perceived social support, reported depressive symptoms were reduced by &#x2212;0.178 points (see <xref ref-type="fig" rid="F2">Figure 2</xref>).</p>
<fig id="F2" position="float">
<label>FIGURE 2</label>
<caption>
<p>Linear regression between social support and depression. Chile, 2021.</p>
</caption>
<graphic xlink:href="ijph-67-1604401-g002.tif"/>
</fig>
<p>To explore the differential effect of each social support dimension on reported depressive symptoms a multiple linear regression was run. This model (<italic>F</italic>(5,176) &#x3d; 7.469, <italic>p</italic> &#x3c; 0.01, <inline-formula id="inf2">
<mml:math id="m2">
<mml:mrow>
<mml:msup>
<mml:mi>R</mml:mi>
<mml:mn>2</mml:mn>
</mml:msup>
</mml:mrow>
</mml:math>
</inline-formula> &#x3d; 0.175), revealed that positive social interactions (<italic>b</italic> &#x3d; &#x2212;0.341, <italic>t</italic>(181) &#x3d; &#x2212;2.177, <italic>p</italic> &#x3d; 0.031) was the only significant predictor of lower depressive symptoms among the other social support dimensions (all other <italic>p</italic>-values &#x3e; 0.05, See <xref ref-type="table" rid="T1">Table 1</xref> for details).</p>
<table-wrap id="T1" position="float">
<label>TABLE 1</label>
<caption>
<p>Analysis of the effect of dimensions of social support on depressive symptoms. Chile, 2021.</p>
</caption>
<table>
<thead valign="top">
<tr>
<th rowspan="2" align="left">Model</th>
<th colspan="2" align="center">Non-standardized coefficients</th>
<th align="center">Standardized coefficients</th>
<th rowspan="2" align="center">t</th>
<th rowspan="2" align="center">
<italic>p</italic>-value</th>
</tr>
<tr>
<th align="center">B</th>
<th align="center">Standard error</th>
<th align="center">Beta</th>
</tr>
</thead>
<tbody valign="top">
<tr>
<td align="left">Constant</td>
<td align="char" char=".">18.63</td>
<td align="char" char=".">2.57</td>
<td align="left"/>
<td align="char" char=".">7.26</td>
<td align="char" char=".">&#x3c;0.001&#x2a;</td>
</tr>
<tr>
<td align="left">MOSS PSI<xref ref-type="table-fn" rid="Tfn1">
<sup>a</sup>
</xref>
</td>
<td align="char" char=".">&#x2212;0.34</td>
<td align="char" char=".">0.16</td>
<td align="char" char=".">&#x2212;0.32</td>
<td align="char" char=".">&#x2212;2.18</td>
<td align="char" char=".">0.031&#x2a;</td>
</tr>
<tr>
<td align="left">MOSS AS<xref ref-type="table-fn" rid="Tfn2">
<sup>b</sup>
</xref>
</td>
<td align="char" char=".">&#x2212;0.28</td>
<td align="char" char=".">0.26</td>
<td align="char" char=".">&#x2212;0.10</td>
<td align="char" char=".">&#x2212;1.04</td>
<td align="char" char=".">0.299</td>
</tr>
<tr>
<td align="left">MOSS IS<xref ref-type="table-fn" rid="Tfn3">
<sup>c</sup>
</xref>
</td>
<td align="char" char=".">&#x2212;0.03</td>
<td align="char" char=".">0.13</td>
<td align="char" char=".">&#x2212;0.02</td>
<td align="char" char=".">&#x2212;0.23</td>
<td align="char" char=".">0.816</td>
</tr>
<tr>
<td align="left">MOSS EIS<xref ref-type="table-fn" rid="Tfn4">
<sup>d</sup>
</xref>
</td>
<td align="char" char=".">0.11</td>
<td align="char" char=".">0.23</td>
<td align="char" char=".">0.06</td>
<td align="char" char=".">0.45</td>
<td align="char" char=".">0.650</td>
</tr>
<tr>
<td align="left">Person&#x2019;s social network</td>
<td align="char" char=".">&#x2212;0.15</td>
<td align="char" char=".">0.09</td>
<td align="char" char=".">&#x2212;0.12</td>
<td align="char" char=".">&#x2212;1.60</td>
<td align="char" char=".">0.112</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn id="Tfn1">
<label>a</label>
<p>Positive Social Interactions.</p>
</fn>
<fn id="Tfn2">
<label>b</label>
<p>Affectionate Support.</p>
</fn>
<fn id="Tfn3">
<label>c</label>
<p>Instrumental Support.</p>
</fn>
<fn id="Tfn4">
<label>d</label>
<p>Emotional/Informational Support.</p>
</fn>
<fn>
<p>&#x2a; Statistically significant (<italic>p &#x3c; 0.05</italic>).</p>
</fn>
</table-wrap-foot>
</table-wrap>
</sec>
<sec id="s3-2">
<title>Association Between Attachment and Depressive Symptoms</title>
<p>A multiple linear regression was run to test the relationship between attachment and reported depressive symptoms. Importantly, these two dimensions of attachment insecurity evidenced no correlation (<italic>r</italic> &#x3d; 0.103, <italic>p</italic> &#x3d; 0.16). The regression showed a significant and positive relationship between depression and ECR-S attachment styles (<italic>F</italic>(1,185) &#x3d;19.786, <italic>p</italic> &#x3c; 0.01) with a <inline-formula id="inf3">
<mml:math id="m3">
<mml:mrow>
<mml:msup>
<mml:mi>R</mml:mi>
<mml:mn>2</mml:mn>
</mml:msup>
</mml:mrow>
</mml:math>
</inline-formula> &#x3d; 0.176. Importantly, both attachment styles resulted as significant coefficients in this model, being avoidance (<italic>b</italic> &#x3d; 0.336, <italic>t</italic>(187) &#x3d; 5.041, <italic>p</italic> &#x3c; 0.01) a slightly stronger predictor than anxiety (<italic>b</italic> &#x3d; 0.192, <italic>t</italic>(187) &#x3d; 3.218, <italic>p</italic> &#x3c; 0.01). Therefore, higher levels of these attachment styles (and therefore, higher levels of attachment insecurity) are related with higher levels of reported depressive symptoms.</p>
</sec>
<sec id="s3-3">
<title>Moderating Effect of Attachment Styles on the Relationship Between Social Support And Depression</title>
<p>A moderated moderation was run to test the role of the two attachment dimensions on the relationship between perceived social support and depression (See a representation in <xref ref-type="sec" rid="s9">Supplementary File S3</xref>). Under this aim, social support scores, insecure attachment dimensions and all the interactions among these predictors were included to explain depression score variance.</p>
<p>As shown in <xref ref-type="table" rid="T2">Table 2</xref>, this analysis evidenced a significant simple effect of avoidance (<italic>t</italic>(180) &#x3d; 2.671, <italic>p</italic> &#x3d; 0.01). The model also showed significant interactions between avoidance and social support (<italic>t</italic>(180) &#x3d; &#x2212;2.854, <italic>p</italic> &#x3c; 0.01), and between the two insecure attachment dimensions (<italic>t</italic>(180) &#x3d; &#x2212;2.583, <italic>p</italic> &#x3d; 0.01). Importantly, the third order interaction with the relevant independent variable and the two moderators was also significant (<italic>t</italic>(180) &#x3d; 2.914, <italic>p</italic> &#x3c; 0.01). This interaction explained a rather small but significant increase in depression variance, &#x394; <inline-formula id="inf4">
<mml:math id="m4">
<mml:mrow>
<mml:msup>
<mml:mi>R</mml:mi>
<mml:mn>2</mml:mn>
</mml:msup>
</mml:mrow>
</mml:math>
</inline-formula> &#x3d; 0.03, <italic>F</italic>(1,180) &#x3d; 8.49, <italic>p</italic> &#x3c; 0.01. Thus, anxiety and avoidance attachment styles are significant moderators of the relationship between social support and depression.</p>
<table-wrap id="T2" position="float">
<label>TABLE 2</label>
<caption>
<p>Moderated moderation model. Chile, 2021.</p>
</caption>
<table>
<thead valign="top">
<tr>
<th colspan="3" align="left">Model Summary</th>
<th colspan="4" align="center">Analysis</th>
<th colspan="4" align="center">Analysis with covariants</th>
</tr>
<tr>
<th colspan="3" align="left">Model</th>
<th align="center">R<sup>2</sup>
</th>
<th align="center">MSE</th>
<th align="center">F</th>
<th align="center">
<italic>p</italic>-value</th>
<th align="center">R<sup>2</sup>
</th>
<th align="center">MSE</th>
<th align="center">F</th>
<th align="center">
<italic>p</italic>-value</th>
</tr>
<tr>
<th rowspan="2" colspan="3" align="left"/>
<th align="center">0.31</th>
<th align="center">20.36</th>
<th align="center">11.69</th>
<th align="center">&#x3c;0.001&#x2a;</th>
<th align="center">0.35</th>
<th align="center">19.37</th>
<th align="center">10.80</th>
<th align="center">&#x3c;0.001&#x2a;</th>
</tr>
<tr>
<th align="center">Coefficient</th>
<th align="center">SE</th>
<th align="center">t</th>
<th align="center">
<italic>p</italic>-value</th>
<th align="center">Coefficient</th>
<th align="center">SE</th>
<th align="center">t</th>
<th align="center">
<italic>p</italic>-value</th>
</tr>
</thead>
<tbody valign="top">
<tr>
<td colspan="3" align="left">Constant</td>
<td align="center">&#x2212;52.20</td>
<td align="center">37.72</td>
<td align="center">&#x2212;1.38</td>
<td align="center">0.168</td>
<td align="center">&#x2212;36.93</td>
<td align="center">37.94</td>
<td align="center">&#x2212;0.97</td>
<td align="center">0.332</td>
</tr>
<tr>
<td colspan="3" align="left">MOSS</td>
<td align="center">0.71</td>
<td align="center">0.46</td>
<td align="center">1.55</td>
<td align="center">0.124</td>
<td align="center">0.55</td>
<td align="center">0.47</td>
<td align="center">1.19</td>
<td align="center">0.236</td>
</tr>
<tr>
<td colspan="3" align="left">ECR-S avoidant</td>
<td align="center">4.24</td>
<td align="center">1.60</td>
<td align="center">2.67</td>
<td align="center">0.008&#x2a;</td>
<td align="center">3.63</td>
<td align="center">1.60</td>
<td align="center">2.26</td>
<td align="center">0.025&#x2a;</td>
</tr>
<tr>
<td colspan="3" align="left">MOSS x ECR-S avoidant</td>
<td align="center">&#x2212;0.06</td>
<td align="center">0.02</td>
<td align="center">&#x2212;2.85</td>
<td align="center">0.005&#x2a;</td>
<td align="center">&#x2212;0.05</td>
<td align="center">0.02</td>
<td align="center">&#x2212;2.37</td>
<td align="center">0.019&#x2a;</td>
</tr>
<tr>
<td colspan="3" align="left">ECR-S anxious</td>
<td align="center">2.77</td>
<td align="center">1.67</td>
<td align="center">1.66</td>
<td align="center">0.100</td>
<td align="center">2.48</td>
<td align="center">1.70</td>
<td align="center">1.46</td>
<td align="center">0.145</td>
</tr>
<tr>
<td colspan="3" align="left">MOSS x ECR-S anxious</td>
<td align="center">&#x2212;0.04</td>
<td align="center">0.02</td>
<td align="center">&#x2212;1.83</td>
<td align="center">0.070</td>
<td align="center">&#x2212;0.03</td>
<td align="center">0.02</td>
<td align="center">&#x2212;1.59</td>
<td align="center">0.114</td>
</tr>
<tr>
<td colspan="3" align="left">ECR-S avoidant x ECR-S anxious</td>
<td align="center">&#x2212;0.18</td>
<td align="center">0.07</td>
<td align="center">&#x2212;2.58</td>
<td align="center">0.011&#x2a;</td>
<td align="center">&#x2212;0.17</td>
<td align="center">0.07</td>
<td align="center">&#x2212;2.29</td>
<td align="center">0.023&#x2a;</td>
</tr>
<tr>
<td colspan="3" align="left">MOSS x ECR-S avoidant x ECR-S anxious</td>
<td align="center">0.003</td>
<td align="center">0.001</td>
<td align="center">2.91</td>
<td align="center">0.004&#x2a;</td>
<td align="center">0.002</td>
<td align="center">0.001</td>
<td align="center">2.55</td>
<td align="center">0.012&#x2a;</td>
</tr>
<tr>
<td colspan="3" align="left">Age</td>
<td align="left"/>
<td align="left"/>
<td align="left"/>
<td align="left"/>
<td align="center">&#x2212;0.07</td>
<td align="center">0.02</td>
<td align="center">&#x2212;3.18</td>
<td align="center">0.009&#x2a;</td>
</tr>
<tr>
<td colspan="3" align="left">Educational level</td>
<td align="left"/>
<td align="left"/>
<td align="left"/>
<td align="left"/>
<td align="center">&#x2212;0.23</td>
<td align="center">0.41</td>
<td align="center">&#x2212;0.56</td>
<td align="center">0.580</td>
</tr>
</tbody>
</table>
<table>
<thead>
<tr>
<td colspan="3" align="left">Conditional effects</td>
<td rowspan="2" align="center">Effect</td>
<td rowspan="2" align="center">SE</td>
<td rowspan="2" align="center">t</td>
<td rowspan="2" align="center">
<italic>p</italic>-value</td>
<td rowspan="2" align="center">Effect</td>
<td rowspan="2" align="center">SE</td>
<td rowspan="2" align="center">t</td>
<td rowspan="2" align="center">
<italic>p</italic>-value</td>
</tr>
<tr>
<td align="left">Level<xref ref-type="table-fn" rid="Tfn5">
<sup>a</sup>
</xref>
</td>
<td align="left">ECR-S avoidant</td>
<td align="left">ECR-S anxious</td>
</tr>
</thead>
<tbody>
<tr>
<td align="left"/>
<td align="left">Low</td>
<td align="left">Low</td>
<td align="center">&#x2212;0.10</td>
<td align="center">0.08</td>
<td align="center">&#x2212;1.35</td>
<td align="center">0.180</td>
<td align="center">&#x2212;0.13</td>
<td align="center">0.08</td>
<td align="center">&#x2212;1.58</td>
<td align="center">0.117</td>
</tr>
<tr>
<td align="left"/>
<td align="left">Low</td>
<td align="left">Medium</td>
<td align="center">&#x2212;0.10</td>
<td align="center">0.05</td>
<td align="center">&#x2212;1.89</td>
<td align="center">0.061</td>
<td align="center">&#x2212;0.13</td>
<td align="center">0.05</td>
<td align="center">&#x2212;2.36</td>
<td align="center">0.019&#x2a;</td>
</tr>
<tr>
<td align="left"/>
<td align="left">Low</td>
<td align="left">High</td>
<td align="center">&#x2212;0.10</td>
<td align="center">0.07</td>
<td align="center">&#x2212;1.32</td>
<td align="center">0.187</td>
<td align="center">&#x2212;0.13</td>
<td align="center">0.07</td>
<td align="center">&#x2212;1.81</td>
<td align="center">0.071</td>
</tr>
<tr>
<td align="left"/>
<td align="left">Medium</td>
<td align="left">Low</td>
<td align="center">&#x2212;0.19</td>
<td align="center">0.05</td>
<td align="center">&#x2212;3.81</td>
<td align="center">&#x3c;0.001&#x2a;</td>
<td align="center">&#x2212;0.19</td>
<td align="center">0.05</td>
<td align="center">&#x2212;3.91</td>
<td align="center">&#x3c;0.001&#x2a;</td>
</tr>
<tr>
<td align="left"/>
<td align="left">Medium</td>
<td align="left">Medium</td>
<td align="center">&#x2212;0.10</td>
<td align="center">0.03</td>
<td align="center">&#x2212;3.02</td>
<td align="center">0.003&#x2a;</td>
<td align="center">&#x2212;0.12</td>
<td align="center">0.03</td>
<td align="center">&#x2212;3.55</td>
<td align="center">&#x3c;0.001&#x2a;</td>
</tr>
<tr>
<td align="left"/>
<td align="left">Medium</td>
<td align="left">High</td>
<td align="center">&#x2212;0.01</td>
<td align="center">0.05</td>
<td align="center">&#x2212;0.29</td>
<td align="center">0.775</td>
<td align="center">&#x2212;0.05</td>
<td align="center">0.05</td>
<td align="center">&#x2212;0.97</td>
<td align="center">0.333</td>
</tr>
<tr>
<td align="left"/>
<td align="left">High</td>
<td align="left">Low</td>
<td align="center">&#x2212;0.28</td>
<td align="center">0.05</td>
<td align="center">&#x2212;5.70</td>
<td align="center">&#x3c;0.001&#x2a;</td>
<td align="center">&#x2212;0.25</td>
<td align="center">0.05</td>
<td align="center">&#x2212;5.43</td>
<td align="center">&#x3c;0.001&#x2a;</td>
</tr>
<tr>
<td align="left"/>
<td align="left">High</td>
<td align="left">Medium</td>
<td align="center">&#x2212;0.11</td>
<td align="center">0.04</td>
<td align="center">&#x2212;3.05</td>
<td align="center">0.003&#x2a;</td>
<td align="center">&#x2212;0.11</td>
<td align="center">0.03</td>
<td align="center">&#x2212;3.42</td>
<td align="center">&#x3c;0.001&#x2a;</td>
</tr>
<tr>
<td align="left"/>
<td align="left">High</td>
<td align="left">High</td>
<td align="center">0.07</td>
<td align="center">0.06</td>
<td align="center">1.22</td>
<td align="center">0.223</td>
<td align="center">0.03</td>
<td align="center">0.05</td>
<td align="center">0.56</td>
<td align="center">0.575</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn id="Tfn5">
<label>a</label>
<p>ECR-S avoidant and anxious scales share three levels: low, medium and high. Mean scores for each level is different for analyzes with and without control for covariates.</p>
</fn>
<fn>
<p>&#x2a;Statistically significant (<italic>p &#x3c; 0.05</italic>).</p>
</fn>
</table-wrap-foot>
</table-wrap>
<p>As reported above, educational level and age resulted in significant correlations with self-reported depression symptoms. Therefore, a new moderated moderation model was run including these two variables as covariates to control for their possible effect. This model evidenced the same significant effects; the simple effect of avoidance and the interaction between this attachment style with social support, and the two insecure attachment dimensions. Importantly, the three order interaction of social support, anxiety and avoidant attachment style was also significant. Regarding the covariates, educational level did not reach the level of significance while age did (<italic>t</italic>(178) &#x3d; &#x2212;3.176, <italic>p</italic> &#x3d; 0.01). As expected, this model still explained a small and significant portion of depression variance, &#x394; <inline-formula id="inf5">
<mml:math id="m5">
<mml:mrow>
<mml:msup>
<mml:mi>R</mml:mi>
<mml:mn>2</mml:mn>
</mml:msup>
</mml:mrow>
</mml:math>
</inline-formula> &#x3d; 0.02, <italic>F</italic>(1,178) &#x3d; 6.48, <italic>p</italic> &#x3d; 0.01.</p>
<p>Through the exploration of the three-way interaction of the model, it is observed that insecure attachment levels (i.e., attachment avoidance and anxiety) impacted the relationship between social support and depression in five different combinations (see <xref ref-type="fig" rid="F3">Figure 3</xref>). Therefore, as detailed in <xref ref-type="table" rid="T2">Table 2</xref>, insecure attachment is a relevant moderator for low and medium levels of avoidance together with low and medium levels of anxiety. Also, for medium levels of both insecure styles, and for high levels of avoidance together with low and medium levels of anxious attachment. These conditional effects evidenced that the negative relationship between social support and depressive symptoms is effective only for certain profiles of insecure attachment. Interestingly, participants scoring high on both avoidant and anxious style have a slight increase of depressive symptoms related to higher levels of social support. Although this result did not reach a significant level, it is important to consider in further studies.</p>
<fig id="F3" position="float">
<label>FIGURE 3</label>
<caption>
<p>Visual result of moderate moderation. Chile, 2021.</p>
</caption>
<graphic xlink:href="ijph-67-1604401-g003.tif"/>
</fig>
</sec>
</sec>
<sec sec-type="discussion" id="s4">
<title>Discussion</title>
<p>We examined the relationship between social support and depression during the COVID-19 pandemic and the role of attachment in this association. As expected, we found that depressive symptoms were lower in people securely attached and in those perceiving themselves as socially supported. In addition, we found that attachment modulated the effect of social support on depressive levels. These associations were not explained by sociodemographic characteristics.</p>
<p>Specifically, lower levels of positive social interactions and higher attachment anxiety and attachment avoidance predicted the greatest depressive symptomatology. More importantly, we found a three-way interaction suggesting a crucial role of attachment styles in the effect of social support on depression. Regarding the association between social support and depression, our findings further corroborated the increasing evidence on the role of social support as a protective factor for depression [<xref ref-type="bibr" rid="B60">60</xref>, <xref ref-type="bibr" rid="B61">61</xref>]. More specifically, the dimension &#x201c;positive social interaction&#x201d; was the strongest predictor of lower depressive symptoms. A possible explanation for this result might be the evidence that the positive social interactions dimension of social support is almost equivalent to the emotional support dimension [<xref ref-type="bibr" rid="B56">56</xref>], which, in turn, has shown to be the most important protective factor against depression in adults [<xref ref-type="bibr" rid="B62">62</xref>].</p>
<p>Another important finding is the association between attachment and depression. Specifically, higher levels of attachment anxiety and avoidance&#x2014;and therefore, levels of attachment insecurity- were related to higher levels of depressive symptomatology. These results are in line with a body of evidence showing the concomitance of depression and attachment insecurity. Several meta-analyses have shown that insecurely attached people are at greater risk for psychopathologies like depression, whilst attachment security constitutes a protective factor that prevents the development of psychopathology [<xref ref-type="bibr" rid="B63">63</xref>, <xref ref-type="bibr" rid="B64">64</xref>]. A recent meta-analysis [<xref ref-type="bibr" rid="B63">63</xref>] concluded that attachment insecurity and depressive symptoms have consistently been shown to be associated (in both longitudinal and cross-sectional studies). The authors state that this association can be explained considering several factors: genetics, as in shared genetic vulnerability for attachment insecurity and depression; cognitive factors, with an internal working model of attachment as the base of dysfunctional cognitions, the core of depression according to Beck [<xref ref-type="bibr" rid="B65">65</xref>]; socio-emotional factors, such as social abilities and emotion regulation; and sociocultural factors, such as shared socio-ecological risk environment [<xref ref-type="bibr" rid="B63">63</xref>].</p>
<p>As noted, attachment and depression are indeed related, and therefore it is pivotal to consider this association when linking social support to depression. The latter brings us to our third hypothesis: the role of attachment in the association between social support and depression. In this regard, as expected, we found a three-way interaction between social support, attachment avoidance, and attachment anxiety in predicting depressive symptoms. Furthermore, this finding suggests that higher levels of social support affect depression that gets modulated by the levels of attachment security. That is to say; social support can have a positive impact and act as a protective factor for depression if there is a presence of security in attachment. These results are novel, and they contribute to the current literature with a more comprehensive understanding of the mechanisms underlying the effect of social support on depression.</p>
<p>This combination of findings supports the conceptual model presented in the introduction section, confirming that social support can be more helpful in preventing mental health problems in people with secure attachment and less useful in people with attachment insecurity.</p>
<p>People with an insecure attachment style perceive their social network as less supportive than people with a secure attachment style [<xref ref-type="bibr" rid="B44">44</xref>]. This perceived lack of support can, in turn, be associated with more depressive symptoms. By contrast, people with secure attachment benefit more from interpersonal relationships [<xref ref-type="bibr" rid="B54">54</xref>], and high-quality interpersonal relationships are a known protective factor for depression [<xref ref-type="bibr" rid="B61">61</xref>].</p>
<p>Regarding specific attachment styles, on the one hand, avoidant attachment is characterised by fear of intimacy and discomfort with closeness [<xref ref-type="bibr" rid="B66">66</xref>], being typical for avoidant people to be unhappy with close relationships. Furthermore, evidence has continually found depressive symptoms linked to a lack of social interaction [<xref ref-type="bibr" rid="B67">67</xref>, <xref ref-type="bibr" rid="B68">68</xref>]. Indeed, social isolation has been postulated as one of the causes of depression [<xref ref-type="bibr" rid="B69">69</xref>&#x2013;<xref ref-type="bibr" rid="B71">71</xref>]. On the other hand, attachment anxiety has been linked with biased and often negative perceptions of social support [<xref ref-type="bibr" rid="B24">24</xref>, <xref ref-type="bibr" rid="B72">72</xref>]. People with anxious attachment styles are characterised by interpersonal suffering regardless of whether or not they have adequate social support [<xref ref-type="bibr" rid="B66">66</xref>]. These negative perceptions of social support might undermine the potential positive effects of social support on mental health.</p>
<p>Additionally, the effect of social support on mental health has been often explained using the stress-buffering model [<xref ref-type="bibr" rid="B73">73</xref>], which states that quality interpersonal relationships act as protective factors of the detrimental effects of stress, mainly through neuroendocrinological mechanisms (e.g., the presence of a significant other dampens the HPA axis stress response) that would modulate the response in front of stressors diminishing depressive symptoms and improving mood [<xref ref-type="bibr" rid="B17">17</xref>, <xref ref-type="bibr" rid="B19">19</xref>]. Our findings align with the buffering stress model, but they go beyond that model by suggesting a fundamental role of attachment in those associations. Since attachment is mainly a system for regulating stress through interpersonal relationships [<xref ref-type="bibr" rid="B2">2</xref>], individual differences in attachment strategies are very likely to modulate how people experience support from their social environment.</p>
<p>Finally, an unexpected finding was the effect of high levels of anxiety and avoidance simultaneously, which showed to revert the association between social support and depression. When both scores were concurrently high, great levels of social support predicted high levels of depressive symptoms. This result can be explained considering the so-called &#x201c;fearful-avoidant&#x201d; attachment style [<xref ref-type="bibr" rid="B74">74</xref>], a specific pattern described in individuals who simultaneously reject engaging in close relationships and have an extreme necessity of being close and loved by others [<xref ref-type="bibr" rid="B74">74</xref>, <xref ref-type="bibr" rid="B75">75</xref>]. Even though the specificity of this pattern is still controversial [<xref ref-type="bibr" rid="B74">74</xref>, <xref ref-type="bibr" rid="B75">75</xref>], evidence has shown fearful avoidance to be related to severe difficulties in emotional regulation within relationships. For example, people with fearful avoidant attachment show a more negative perception of others&#x2019; support [<xref ref-type="bibr" rid="B76">76</xref>] and less commitment and satisfaction in romantic relationships [<xref ref-type="bibr" rid="B77">77</xref>, <xref ref-type="bibr" rid="B78">78</xref>]. In this way, these results may be related to the negative experience of close relationships that can trigger interpersonal conflict. It is known that some people can score high in social support and at the same time present negative health outcomes [<xref ref-type="bibr" rid="B79">79</xref>, <xref ref-type="bibr" rid="B80">80</xref>], especially when they experience their social network as containing both positive and negative experiences (e.g., experienced interpersonal conflict).</p>
<p>In sum, our results confirm the role of social support on depression and add to the current literature by connecting attachment security as an essential factor to include in our current understanding of relationships and mental health.</p>
<p>Although greater levels of social support were associated with lower levels of depression we cannot definitively conclude that social support alone accounted for this effect. Other uncontrolled variables, such as the type of householding during the pandemic lockdown, levels of physical activity, concomitant chronic or other unknown variables may have contributed to this effect. In addition, more precise measurements (i.e., not only self-report questionnaires) of our variables than what we used and further measurements over time would be needed to confirm these associations.</p>
<p>Our study variables are complex, and they relate to several psychosocial phenomena. Future studies should explore the role of other individual differences that might influence the perception of social support (e.g., personality) and control factors that affect depressive symptoms (e.g., diagnosis and treatment). Other limitations of our work include the sampling method (snowball convenience) and the lack of specific tools measuring aspects related to the COVID-19 pandemic (e.g., stress levels).</p>
<p>Taken together, our findings demonstrate that attachment has a key role in the individual differences in the effect of social support on depressive symptoms. Health interventions for depression have not yet addressed the therapeutic potential of social relationships efficiently [<xref ref-type="bibr" rid="B81">81</xref>] despite the amount of evidence showing its role in depression [<xref ref-type="bibr" rid="B60">60</xref>, <xref ref-type="bibr" rid="B62">62</xref>]. Our results suggest that integrating attachment theory within social support approaches can provide a compelling framework for studying and developing treatments considering the role of interpersonal relationships in depression in a more meaningful and applicable way.</p>
<p>Further research might explore the clinical usefulness of these findings, analysing the evolution of the variables assessed in this study throughout therapeutic processes.</p>
</sec>
</body>
<back>
<sec id="s5">
<title>Ethics Statement</title>
<p>The studies involving human participants were reviewed and approved by the Comit&#xe9; de &#xc9;tica, Universidad del Desarrollo. The patients/participants provided their written informed consent to participate in this study.</p>
</sec>
<sec id="s6">
<title>Author Contributions</title>
<p>Designed the research: SC-C, AV-C, and JS. Supervised research: SC-C and AR. Perform research: AV-C, SC-C, and CA-R. Analyzed the data: AV-C. Wrote the manuscript: SC-C, CA-R, AR, and AV-C.</p>
</sec>
<sec id="s7">
<title>Funding</title>
<p>The present work was financed by Agencia Nacional de Investigaci&#xf3;n y Desarrollo (ANID, Chile) through FONDECYT regular No. 1190610 to AR. This study also received funding from ANID&#x2014;Iniciativa Cient&#xed;fica Milenio, Instituto Milenio para la Investigaci&#xf3;n en Depresi&#xf3;n y Personalidad (MIDAP) and FONDECYT No. 1221538. The funder was not involved in the study design, collection, analysis, interpretation of data, the writing of this article or the decision to submit it for publication.</p>
</sec>
<sec sec-type="COI-statement" id="s8">
<title>Conflict of Interest</title>
<p>The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<ack>
<p>We thank Franco Medina for useful discussions.</p>
</ack>
<sec id="s9">
<title>Supplementary Material</title>
<p>The Supplementary Material for this article can be found online at: <ext-link ext-link-type="uri" xlink:href="https://www.ssph-journal.org/articles/10.3389/ijph.2022.1604401/full#supplementary-material">https://www.ssph-journal.org/articles/10.3389/ijph.2022.1604401/full&#x23;supplementary-material</ext-link>
</p>
<supplementary-material xlink:href="DataSheet2.docx" id="SM1" mimetype="application/docx" xmlns:xlink="http://www.w3.org/1999/xlink"/>
<supplementary-material xlink:href="DataSheet1.docx" id="SM2" mimetype="application/docx" xmlns:xlink="http://www.w3.org/1999/xlink"/>
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