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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Int J Public Health</journal-id>
<journal-title>International Journal of Public Health</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Int J Public Health</abbrev-journal-title>
<issn pub-type="epub">1661-8564</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">1605786</article-id>
<article-id pub-id-type="doi">10.3389/ijph.2023.1605786</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Public Health Archive</subject>
<subj-group>
<subject>Original Article</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Type of Refugee Accommodation and Health of Residents: A Cross-Sectional, Population-Based Cluster Analysis in South-West Germany</article-title>
<alt-title alt-title-type="left-running-head">Mohsenpour et al.</alt-title>
<alt-title alt-title-type="right-running-head">Refugee Accommodation and Health</alt-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes" equal-contrib="yes">
<name>
<surname>Mohsenpour</surname>
<given-names>Amir</given-names>
</name>
<xref ref-type="aff" rid="aff1">
<sup>1</sup>
</xref>
<xref ref-type="corresp" rid="c001">&#x2a;</xref>
<xref ref-type="fn" rid="fn1">
<sup>&#x2020;</sup>
</xref>
<uri xlink:href="https://loop.frontiersin.org/people/1608374/overview"/>
</contrib>
<contrib contrib-type="author" equal-contrib="yes">
<name>
<surname>Dudek</surname>
<given-names>Verena</given-names>
</name>
<xref ref-type="aff" rid="aff2">
<sup>2</sup>
</xref>
<xref ref-type="fn" rid="fn1">
<sup>&#x2020;</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Bozorgmehr</surname>
<given-names>Kayvan</given-names>
</name>
<xref ref-type="aff" rid="aff1">
<sup>1</sup>
</xref>
<xref ref-type="aff" rid="aff3">
<sup>3</sup>
</xref>
<uri xlink:href="https://loop.frontiersin.org/people/2139801/overview"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Biddle</surname>
<given-names>Louise</given-names>
</name>
<xref ref-type="aff" rid="aff1">
<sup>1</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Razum</surname>
<given-names>Oliver</given-names>
</name>
<xref ref-type="aff" rid="aff2">
<sup>2</sup>
</xref>
<uri xlink:href="https://loop.frontiersin.org/people/306965/overview"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Sauzet</surname>
<given-names>Odile</given-names>
</name>
<xref ref-type="aff" rid="aff2">
<sup>2</sup>
</xref>
<xref ref-type="aff" rid="aff4">
<sup>4</sup>
</xref>
<uri xlink:href="https://loop.frontiersin.org/people/595878/overview"/>
</contrib>
</contrib-group>
<aff id="aff1">
<sup>1</sup>
<institution>Population Medicine and Health Services Research</institution>, <institution>School of Public Health</institution>, <institution>Bielefeld University</institution>, <addr-line>Bielefeld</addr-line>, <country>Germany</country>
</aff>
<aff id="aff2">
<sup>2</sup>
<institution>Epidemiology and International Public Health</institution>, <institution>School of Public Health</institution>, <institution>Bielefeld University</institution>, <addr-line>Bielefeld</addr-line>, <country>Germany</country>
</aff>
<aff id="aff3">
<sup>3</sup>
<institution>Section for Health Equity Studies and Migration</institution>, <institution>Department of General Practice and Health Services Research</institution>, <institution>Heidelberg University Hospital</institution>, <institution>Marsilius Arkaden</institution>, <addr-line>Heidelberg</addr-line>, <country>Germany</country>
</aff>
<aff id="aff4">
<sup>4</sup>
<institution>Data Analysis Group</institution>, <institution>Department of Business Administration and Economics</institution>, <institution>Bielefeld University</institution>, <addr-line>Bielefeld</addr-line>, <country>Germany</country>
</aff>
<author-notes>
<fn fn-type="edited-by">
<p>
<bold>Edited by:</bold> <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/2145676/overview">Charles Abongomera</ext-link>, Swiss Tropical and Public Health Institute, Switzerland</p>
</fn>
<fn fn-type="edited-by">
<p>
<bold>Reviewed by:</bold> <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/880672/overview">Alessandra Costanza</ext-link>, University of Geneva, Switzerland</p>
<p>
<ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/1037195/overview">Christian Janssen</ext-link>, Munich University of Applied Sciences, Germany</p>
</fn>
<corresp id="c001">&#x2a;Correspondence: Amir Mohsenpour, <email>amir.mohsenpour@uni-bielefeld.de</email>
</corresp>
<fn id="fn001" fn-type="other">
<p>This Original Article is part of the IJPH Special Issue &#x201c;Migration Health Around the Globe&#x2014;A Construction Site With Many Challenges&#x201d;</p>
</fn>
<fn fn-type="equal" id="fn1">
<label>
<sup>&#x2020;</sup>
</label>
<p>These authors have contributed equally to this work</p>
</fn>
</author-notes>
<pub-date pub-type="epub">
<day>06</day>
<month>09</month>
<year>2023</year>
</pub-date>
<pub-date pub-type="collection">
<year>2023</year>
</pub-date>
<volume>68</volume>
<elocation-id>1605786</elocation-id>
<history>
<date date-type="received">
<day>15</day>
<month>01</month>
<year>2023</year>
</date>
<date date-type="accepted">
<day>21</day>
<month>08</month>
<year>2023</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#xa9; 2023 Mohsenpour, Dudek, Bozorgmehr, Biddle, Razum and Sauzet.</copyright-statement>
<copyright-year>2023</copyright-year>
<copyright-holder>Mohsenpour, Dudek, Bozorgmehr, Biddle, Razum and Sauzet</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p>
</license>
</permissions>
<abstract>
<p>
<bold>Objectives:</bold> Few studies have assessed whether refugees&#x2019; health is associated with accommodation characteristics. We aimed to devise a typology of refugee accommodation based on variables on the accommodation and its physical context before assessing its association with health in multivariate analyses.</p>
<p>
<bold>Methods:</bold> We performed a cluster analysis based on a hierarchal, agglomerative clustering algorithm using Euclidean Distance and Ward&#x2019;s method. We analysed accommodation clusters based on number of inhabitants, degree of housing deterioration, urbanity of location (urban/rural distinction), and remoteness (walking distance to shops, medical or administrative services). In total, we analysed health and accommodation data of 412 refugees and asylum seekers from 58 different accommodation facilities in the federal state of Baden-W&#xfc;rttemberg in the south-west of Germany.</p>
<p>
<bold>Results:</bold> Accommodations with a moderate occupation, lowest levels of deterioration, and a central urban location showed the best health outcomes in terms of subjective general health status, depression, and generalized anxiety disorder (GAD). Associations were strongest for GAD and weakest for depression.</p>
<p>
<bold>Conclusion:</bold> Our findings inform policymakers on layout and location of refugee collective accommodation centres.</p>
</abstract>
<kwd-group>
<kwd>refugees</kwd>
<kwd>asylum seekers</kwd>
<kwd>neighbourhoods</kwd>
<kwd>mental health</kwd>
<kwd>accommodation</kwd>
</kwd-group>
</article-meta>
</front>
<body>
<sec sec-type="intro" id="s1">
<title>Introduction</title>
<p>Living conditions of refugees and asylum seekers in resettlement countries are considered as post-migration conditions that can generate stress [<xref ref-type="bibr" rid="B1">1</xref>]. While common mental disorders are highly prevalent in collective accommodation centres [<xref ref-type="bibr" rid="B2">2</xref>], studies rarely investigate the impact of the accommodation itself. Living in large reception centres significantly predicted mental problems among unaccompanied minors in the Netherlands [<xref ref-type="bibr" rid="B3">3</xref>]; adult residents in state-provided reception centres suffered from poorer mental health than residents in other accommodation types [<xref ref-type="bibr" rid="B4">4</xref>]. Ajlan considered collective accommodation centres as &#x201c;unhomely places&#x201d; in which the lack of privacy and autonomy creates uncertainty and desperation potentially causing violence among residents [<xref ref-type="bibr" rid="B5">5</xref>]. Further, the COVID-19 pandemic has illustrated the particular physical health risks of living in collective accommodation centres [<xref ref-type="bibr" rid="B6">6</xref>, <xref ref-type="bibr" rid="B7">7</xref>].</p>
<p>While there is substantial evidence indicating that the type of accommodation can impact residents&#x2019; health, it is less well understood which contextual factors or combination thereof are most important in this association. Germany offers an informative setting to examine this question because of the broad range of accommodation types even within one federal state. In the past years, the number of refugees and asylum seekers living in German collective accommodation centres has declined [<xref ref-type="bibr" rid="B8">8</xref>, <xref ref-type="bibr" rid="B9">9</xref>], but every fourth was still living in collective accommodation at the end of 2019 [<xref ref-type="bibr" rid="B8">8</xref>, <xref ref-type="bibr" rid="B9">9</xref>]. These centres can be divided into initial reception centres, including arrival- and AnkER-centres, with compulsory residence until refugee status is determined (but for maximum of 18 months), and subsequent collective accommodation centres. For further clarification, AnkER-centres are special types of reception centres concentrating all relevant actors for the reception, Germany-wide distribution, and (where relevant) the deportation of asylum seekers in one site. This concept is mainly implemented in Bavaria. In the following manuscript, the term &#x201c;collective accommodation centre&#x201d; is used to denote initial reception centres as well as subsequent collective accommodation unless a distinction is necessary. The size and layout of German collective accommodation centres differ in many ways. In the federal state of North Rhine-Westphalia, for example, capacities of state-mandated reception centres ranged from 160 to more than 1,000 people in 2019 [<xref ref-type="bibr" rid="B10">10</xref>]. In 2016, many residents were housed in re-dedicated buildings, such as former offices, schools or hotels [<xref ref-type="bibr" rid="B11">11</xref>], each entailing specific and often poor housing conditions. Around one-third were situated in rural areas and around one-quarter in non-residential industrial areas [<xref ref-type="bibr" rid="B12">12</xref>]. Moreover, accommodation centres often were located in non-residential areas, far away from infrastructure, contributing to the social exclusion of the residents [<xref ref-type="bibr" rid="B5">5</xref>].</p>
<p>In this paper, we aimed to devise a typology of refugee accommodation which helps to examine potential context-related health differences, using a large German federal state as example. We then used this typology to analyse possible associations between accommodation types and the health of their residents.</p>
</sec>
<sec sec-type="methods" id="s2">
<title>Methods</title>
<sec id="s2-1">
<title>Data</title>
<p>We analysed health and accommodation data of 412 refugees and asylum seekers from up to 58 different accommodation facilities in the federal state of Baden-W&#xfc;rttemberg in the south-west of Germany, collected in the RESPOND study [<xref ref-type="bibr" rid="B12">12</xref>]. For the latter, RESPOND researchers developed and validated an instrument, the &#x201c;Small-area Housing Environment Deterioration&#x201d; (SHED) index assessing different domains of housing and its physical environment [<xref ref-type="bibr" rid="B13">13</xref>]. The geographical location was specified at district level. A binary variable indicated population density; &#x3c;150 inhabitants per km<sup>2</sup> was considered as rural, else urban, following the standard BBSR (Federal Institute for Research on Building, Urban Affairs and Spatial Development) definition. The distances to shops, medical and administrative services by foot and with public transport was estimated using Google Maps (GM) routes. Besides accommodation variables, the RESPOND study has also assessed a range of (subjective) physical and mental health outcomes, including a screening of GAD, depression symptoms, and the subjective general health status [<xref ref-type="bibr" rid="B12">12</xref>]. They were measured using the Generalized Anxiety Disorder GAD-2 [<xref ref-type="bibr" rid="B14">14</xref>], the Patient Health Questionnaire PHQ-2 for depression [<xref ref-type="bibr" rid="B15">15</xref>] as well as a general health indicator drawn from the European Health Interview Survey (EHIS), [<xref ref-type="bibr" rid="B16">16</xref>].</p>
</sec>
<sec id="s2-2">
<title>Statistical Methods</title>
<p>We performed a cluster analysis with the RESPOND variables that contained information about the accommodation and its physical context, i.e., the number of inhabitants, remoteness (walking distance to shops, medical or administrative services), urbanity (urban/rural distinction), and housing decay. For the latter, the overall SHED score as well as the normalized and z-standardized single scores were included in the analysis to identify housing differences. After exploring different cluster algorithms and methods, we chose a hierarchal, agglomerative clustering algorithm using Euclidean Distance and Ward&#x2019;s method. We identified the number of clusters by visually assessing dendrogram and scatterplot, before adding the clusters as separate variables to the data set, representing different accommodation types. Additional thorough descriptive statistics were reported in previous articles [<xref ref-type="bibr" rid="B12">12</xref>, <xref ref-type="bibr" rid="B17">17</xref>]. After bivariate analyses between clusters and health outcomes, we performed logistic regression analyses to obtain associations between the identified accommodation clusters and binary measures of general health, GAD, and depression adjusted for potential confounders. Both PHQ and GAD were dichotomised with scores above a cut-off value of 3 considered to be indicative of a depressive or anxiety disorder, respectively. General health was measured on a 5-point Likert scale and dichotomised at a cut-off value of 3 and upwards. The independent variables included age, gender, and the cluster variables. In subsequent analyses, we assessed how the distribution of GAD and depression differed between the clusters. We created three distribution variables (GAD or depression present, both present, both absent) and used these distribution variables as dependent variables in additional logistic regression analyses. All statistical analyses were performed with R (version 3.6.2).</p>
</sec>
</sec>
<sec sec-type="results" id="s3">
<title>Results</title>
<sec id="s3-1">
<title>Clustering</title>
<p>Descriptive statistics of the variables included in the cluster analysis are provided in <xref ref-type="table" rid="T1">Table 1</xref>. Complete accommodation data of 411 refugees and asylum seekers were included in the cluster analysis. The resulting dendrogram and scatterplot pointed to either two or four clusters. To keep the within-group variance of the agglomerated clusters as high as possible, we decided to construct four clusters. A two-cluster solution would have led to a high level of dissimilarity. Cluster 1 and 3 were the smallest, containing 39 respondents of the RESPOND study each (from two and nine different accommodation centres, respectively). Cluster 4 contained 143 respondents from 29 different accommodation centres, and Cluster 2 190 respondents from 29 accommodation centres.</p>
<table-wrap id="T1" position="float">
<label>TABLE 1</label>
<caption>
<p>Cluster characteristics of refugee accommodation (Baden-Wuerttemberg, Germany. 2018 [<xref ref-type="bibr" rid="B12">12</xref>]).</p>
</caption>
<table>
<thead valign="top">
<tr>
<th rowspan="2" colspan="2" align="left"/>
<th colspan="5" align="center">Cluster</th>
</tr>
<tr>
<th align="center">1</th>
<th align="center">2</th>
<th align="center">3</th>
<th align="center">4</th>
<th align="center">Total</th>
</tr>
</thead>
<tbody valign="top">
<tr>
<td colspan="7" align="left">Age of the residents</td>
</tr>
<tr>
<td align="left">&#x2003;Mean</td>
<td align="left"/>
<td align="center">31.5</td>
<td align="center">31.8</td>
<td align="center">33.1</td>
<td align="center">33.4</td>
<td align="center">32.45</td>
</tr>
<tr>
<td align="left">&#x2003;SD</td>
<td align="left"/>
<td align="center">7.2</td>
<td align="center">12</td>
<td align="center">10.4</td>
<td align="center">9.9</td>
<td align="center">9.88</td>
</tr>
<tr>
<td align="left">&#x2003;Missings</td>
<td align="center">
<italic>n</italic>
</td>
<td align="center">1</td>
<td align="center">17</td>
<td align="center">5</td>
<td align="center">28</td>
<td align="center">51</td>
</tr>
<tr>
<td colspan="7" align="left">Sex of the residents</td>
</tr>
<tr>
<td rowspan="2" align="left">&#x2003;Male</td>
<td align="center">
<italic>n</italic>
</td>
<td align="center">19</td>
<td align="center">131</td>
<td align="center">21</td>
<td align="center">81</td>
<td rowspan="2" align="center">252</td>
</tr>
<tr>
<td align="center">%</td>
<td align="center">51.4</td>
<td align="center">77.5</td>
<td align="center">61.8</td>
<td align="center">63.8</td>
</tr>
<tr>
<td rowspan="2" align="left">&#x2003;Female</td>
<td align="center">
<italic>n</italic>
</td>
<td align="center">18</td>
<td align="center">38</td>
<td align="center">13</td>
<td align="center">46</td>
<td rowspan="2" align="center">115</td>
</tr>
<tr>
<td align="center">%</td>
<td align="center">48.6</td>
<td align="center">22.5</td>
<td align="center">38.2</td>
<td align="center">36.2</td>
</tr>
<tr>
<td align="left">&#x2003;Missings</td>
<td align="center">
<italic>n</italic>
</td>
<td align="center">2</td>
<td align="center">21</td>
<td align="center">5</td>
<td align="center">16</td>
<td align="center">44</td>
</tr>
<tr>
<td colspan="7" align="left">No. of inhabitants</td>
</tr>
<tr>
<td align="left">&#x2003;Mean</td>
<td align="left"/>
<td align="center">150.6</td>
<td align="center">69.7</td>
<td align="center">14.6</td>
<td align="center">26.7</td>
<td align="center">65.4</td>
</tr>
<tr>
<td align="left">&#x2003;SD</td>
<td align="left"/>
<td align="center">9</td>
<td align="center">20.9</td>
<td align="center">7.5</td>
<td align="center">13.6</td>
<td align="center">12.75</td>
</tr>
<tr>
<td colspan="7" align="left">Remoteness</td>
</tr>
<tr>
<td colspan="7" align="left">Remoteness: medical services (in minutes walking)</td>
</tr>
<tr>
<td align="left">&#x2003;Mean</td>
<td align="left"/>
<td align="center">14.1</td>
<td align="center">12.9</td>
<td align="center">54.2</td>
<td align="center">14.8</td>
<td align="center">24</td>
</tr>
<tr>
<td align="left">&#x2003;SD</td>
<td align="left"/>
<td align="center">2.5</td>
<td align="center">5.3</td>
<td align="center">15.3</td>
<td align="center">13.8</td>
<td align="center">9.23</td>
</tr>
<tr>
<td colspan="7" align="left">Remoteness: administrative services (in minutes walking)</td>
</tr>
<tr>
<td align="left">&#x2003;Mean</td>
<td align="left"/>
<td align="center">16.2</td>
<td align="center">21.6</td>
<td align="center">50.5</td>
<td align="center">17.4</td>
<td align="center">26.43</td>
</tr>
<tr>
<td align="left">&#x2003;SD</td>
<td align="left"/>
<td align="center">7.5</td>
<td align="center">10.3</td>
<td align="center">12.5</td>
<td align="center">19.5</td>
<td align="center">12.45</td>
</tr>
<tr>
<td colspan="7" align="left">Remoteness: Shops (in minutes walking)</td>
</tr>
<tr>
<td align="left">&#x2003;Mean</td>
<td align="left"/>
<td align="center">15.2</td>
<td align="center">9.3</td>
<td align="center">56.5</td>
<td align="center">10.6</td>
<td align="center">22.9</td>
</tr>
<tr>
<td align="left">&#x2003;SD</td>
<td align="left"/>
<td align="center">1.5</td>
<td align="center">5.2</td>
<td align="center">15.1</td>
<td align="center">8.3</td>
<td align="center">7.53</td>
</tr>
<tr>
<td colspan="7" align="left">Urbanity</td>
</tr>
<tr>
<td rowspan="2" align="left">&#x2003;Rural</td>
<td align="center">
<italic>n</italic>
</td>
<td align="center">0</td>
<td align="center">53</td>
<td align="center">4</td>
<td align="center">38</td>
<td rowspan="2" align="center">95</td>
</tr>
<tr>
<td align="center">%</td>
<td align="center">0</td>
<td align="center">27.9</td>
<td align="center">10.3</td>
<td align="center">26.6</td>
</tr>
<tr>
<td rowspan="2" align="left">&#x2003;Urban (&#x2265;150 inhabitants per km<sup>2</sup>)</td>
<td align="center">
<italic>n</italic>
</td>
<td align="center">39</td>
<td align="center">137</td>
<td align="center">35</td>
<td align="center">105</td>
<td rowspan="2" align="center">316</td>
</tr>
<tr>
<td align="center">%</td>
<td align="center">100</td>
<td align="center">72.1</td>
<td align="center">89.7</td>
<td align="center">73.4</td>
</tr>
<tr>
<td colspan="7" align="left">Small-area Housing Environment Deterioration (SHED)</td>
</tr>
<tr>
<td colspan="7" align="left">SHED total score</td>
</tr>
<tr>
<td align="left">&#x2003;Mean</td>
<td align="left"/>
<td align="center">3.6</td>
<td align="center">1.1</td>
<td align="center">0.8</td>
<td align="center">0.8</td>
<td align="center">1.58</td>
</tr>
<tr>
<td align="left">&#x2003;SD</td>
<td align="left"/>
<td align="center">1.5</td>
<td align="center">0.8</td>
<td align="center">0.7</td>
<td align="center">0.9</td>
<td align="center">0.98</td>
</tr>
<tr>
<td colspan="7" align="left">SHED: broken windows<xref ref-type="table-fn" rid="Tfn1">
<sup>a</sup>
</xref>
</td>
</tr>
<tr>
<td align="left">&#x2003;Mean</td>
<td align="left"/>
<td align="center">0.4</td>
<td align="center">0.0</td>
<td align="center">0.2</td>
<td align="center">0.0</td>
<td align="center">0.15</td>
</tr>
<tr>
<td align="left">&#x2003;SD</td>
<td align="left"/>
<td align="center">0.3</td>
<td align="center">0.1</td>
<td align="center">0.3</td>
<td align="center">0.1</td>
<td align="center">0.2</td>
</tr>
<tr>
<td colspan="7" align="left">SHED: walls<xref ref-type="table-fn" rid="Tfn1">
<sup>a</sup>
</xref>
</td>
</tr>
<tr>
<td align="left">&#x2003;Mean</td>
<td align="left"/>
<td align="center">0.5</td>
<td align="center">0.2</td>
<td align="center">0.1</td>
<td align="center">0.1</td>
<td align="center">0.23</td>
</tr>
<tr>
<td align="left">&#x2003;SD</td>
<td align="left"/>
<td align="center">0.2</td>
<td align="center">0.2</td>
<td align="center">0.2</td>
<td align="center">0.2</td>
<td align="center">0.2</td>
</tr>
<tr>
<td colspan="7" align="left">SHED: graffities<xref ref-type="table-fn" rid="Tfn1">
<sup>a</sup>
</xref>
</td>
</tr>
<tr>
<td align="left">&#x2003;Mean</td>
<td align="left"/>
<td align="center">0.5</td>
<td align="center">0.2</td>
<td align="center">0</td>
<td align="center">0.1</td>
<td align="center">0.2</td>
</tr>
<tr>
<td align="left">&#x2003;SD</td>
<td align="left"/>
<td align="center">0</td>
<td align="center">0.3</td>
<td align="center">0</td>
<td align="center">0.2</td>
<td align="center">0.13</td>
</tr>
<tr>
<td colspan="7" align="left">SHED: outside space<xref ref-type="table-fn" rid="Tfn1">
<sup>a</sup>
</xref>
</td>
</tr>
<tr>
<td align="left">&#x2003;Mean</td>
<td align="left"/>
<td align="center">0.8</td>
<td align="center">0.1</td>
<td align="center">0.1</td>
<td align="center">0.1</td>
<td align="center">0.28</td>
</tr>
<tr>
<td align="left">&#x2003;SD</td>
<td align="left"/>
<td align="center">0.2</td>
<td align="center">0.2</td>
<td align="center">0.2</td>
<td align="center">0.3</td>
<td align="center">0.23</td>
</tr>
<tr>
<td colspan="7" align="left">SHED: garbage accumulation<xref ref-type="table-fn" rid="Tfn1">
<sup>a</sup>
</xref>
</td>
</tr>
<tr>
<td align="left">&#x2003;Mean</td>
<td align="left"/>
<td align="center">0.8</td>
<td align="center">0.3</td>
<td align="center">0</td>
<td align="center">0.2</td>
<td align="center">0.33</td>
</tr>
<tr>
<td align="left">&#x2003;SD</td>
<td align="left"/>
<td align="center">0.2</td>
<td align="center">0.2</td>
<td align="center">0.1</td>
<td align="center">0.3</td>
<td align="center">0.2</td>
</tr>
<tr>
<td colspan="7" align="left">SHED: overall rating physical environment<xref ref-type="table-fn" rid="Tfn1">
<sup>a</sup>
</xref>
</td>
</tr>
<tr>
<td align="left">&#x2003;Mean</td>
<td align="left"/>
<td align="center">0.6</td>
<td align="center">0.3</td>
<td align="center">0.3</td>
<td align="center">0.3</td>
<td align="center">0.38</td>
</tr>
<tr>
<td align="left">&#x2003;SD</td>
<td align="left"/>
<td align="center">0.5</td>
<td align="center">0.3</td>
<td align="center">0.3</td>
<td align="center">0.3</td>
<td align="center">0.35</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn id="Tfn1">
<label>
<sup>a</sup>
</label>
<p>0&#x2013;1 normalized and z-standardized SHED single items.</p>
</fn>
</table-wrap-foot>
</table-wrap>
</sec>
<sec id="s3-2">
<title>Cluster Characteristics</title>
<sec id="s3-2-1">
<title>Cluster 1</title>
<p>Respondents in Cluster 1 had a mean age of 31.5&#xa0;years (SD &#x3d; 7.2), and 48.6% were female. In all other clusters, the proportion of women was lower. With an average of 151 residents per accommodation (SD &#x3d; 9.0), Cluster 1 included the largest type of accommodation analysed here. The total SHED-score was 3.6 (SD &#x3d; 1.5) which was higher than in all other clusters, indicating the highest level of housing deterioration. Besides the broken-windows indicator, all other single indicators scored equal to or larger than 0.5. Garbage accumulation and the outward appearance were most striking with a score of 0.8 each (SD &#x3d; 0.2). Both accommodation centres in Cluster 1 were in an urban district according to the BBSR definition. Shops, medical and administrative services could all be reached by foot in around 15&#xa0;min (SD &#x2264; 7.5).</p>
<p>Key characteristics of cluster 1:<list list-type="simple">
<list-item>
<p>- Largest accommodation type</p>
</list-item>
<list-item>
<p>- Highest state of decay</p>
</list-item>
<list-item>
<p>- Urban and central location</p>
</list-item>
</list>
</p>
</sec>
<sec id="s3-2-2">
<title>Cluster 2</title>
<p>Respondents in Cluster 2 had a mean age of 31.8&#xa0;years (SD &#x3d; 12). With a percentage of 22.5%, the proportion of women was the lowest of all clusters. This cluster had an average number of 70 residents per accommodation (SD &#x3d; 20.9), including the second largest accommodation type. Housing deterioration was lower than in Cluster 1 but with a SHED-score of 1.1 (SD &#x3d; 0.8) it was the cluster with the second highest state of decay. Garbage accumulation and the overall evaluation of the physical environment scored highest but with only 0.3 each (SD &#x2264; 0.3). Most of the 14 accommodation centres in this cluster were located in urban districts. Still, the percentage of residents living in urban areas was the lowest with only 72.1%. Shops and medical services could be accessed within approximately 10&#xa0;min each by foot (SD &#x2248; 5), distance to administrative services was larger with around 22&#xa0;min (SD &#x3d; 10.3).</p>
<p>Key characteristics cluster 2:<list list-type="simple">
<list-item>
<p>- Second largest accommodation type</p>
</list-item>
<list-item>
<p>- Second highest state of decay</p>
</list-item>
<list-item>
<p>- Partly located in rural districts but still central</p>
</list-item>
</list>
</p>
</sec>
<sec id="s3-2-3">
<title>Cluster 3</title>
<p>In Cluster 3, respondents were slightly older than in the other clusters with a mean age of 33.1&#xa0;years (SD &#x3d; 10.4), 38.2% being female. With 15 residents on average (SD &#x3d; 7.5), Cluster 3 presented the smallest accommodation type. It also showed one of the lowest SHED-scores with 0.8 (SD &#x3d; 0.7). The overall evaluation of the physical environment scored highest at 0.3 (SD &#x3d; 0.3), all other dimensions were close to zero. Though up to 90% of the accommodation centres (<italic>n</italic> &#x3d; 9) can be considered as being located in urban districts, remoteness levels were remarkably high, with walking distances to shops, medical and administrative services being larger than 50&#xa0;min (SD &#x2264; 15.3).</p>
<p>Key characteristics of cluster 3:<list list-type="simple">
<list-item>
<p>- Smallest accommodation type</p>
</list-item>
<list-item>
<p>- Low state of decay</p>
</list-item>
<list-item>
<p>- Located in urban districts but in the outskirts</p>
</list-item>
</list>
</p>
</sec>
<sec id="s3-2-4">
<title>Cluster 4</title>
<p>In Cluster 4, respondents were the oldest with a mean age of 33.4&#xa0;years (SD &#x3d; 9.9); 36.2% were female. This cluster included some of the smaller accommodation types with an average of 27 residents (SD &#x3d; 13.6). With an overall SHED-score of 0.8 (SD &#x3d; 0.9) and the highest single indicator being the overall evaluation of the physical environment (0.3, SD &#x3d; 0.3), Cluster 4 presented quite similar low scores for housing deterioration as Cluster 3. The proportion of accommodation centres being located in urban districts was similarly low as in Cluster 2 with approximately 73%. Shops could be reached by foot within 11&#xa0;min (SD &#x3d; 8.3), medical services within 15&#xa0;min (SD &#x3d; 13.8) and administrative services within 17&#xa0;min, though a standard deviation of 19.5 indicated relatively high variations here.</p>
<p>Key characteristics of cluster 4:<list list-type="simple">
<list-item>
<p>- Small accommodation type</p>
</list-item>
<list-item>
<p>- Low state of decay</p>
</list-item>
<list-item>
<p>- Partly located in rural districts but still central</p>
</list-item>
</list>
</p>
<p>More details of the cluster characteristics are provided in <xref ref-type="table" rid="T1">Table 1</xref>. In sum, the four clusters can roughly be divided into two larger accommodation types with deteriorated conditions and two smaller accommodation types with a low level of housing deterioration. The highest SHED-score was 3.6 out of a maximum of 6, indicating no extreme levels of housing deterioration. Scores for garbage accumulation were higher in the two clusters with a larger number of inhabitants, the same also applies to a lesser extent to the graffiti-score. In contrast, graffities and garbage accumulation were of little concern in the smallest accommodation cluster. All accommodation types were predominantly located in urban districts based on the urban-rural distinction applied here. Considering the level of remoteness, the results of Clusters 1, 2 and 4 were fairly similar, all showing acceptable distances to shops and essential services. Cluster 3, by contrast, was comparatively remote with walking distances beyond 50&#xa0;min.</p>
</sec>
</sec>
<sec id="s3-3">
<title>Health Disparities Between Clusters</title>
<p>Descriptive statistics of the health outcomes are provided by clusters in <xref ref-type="table" rid="T2">Table 2</xref>. The four clusters showed differences in the health status of their respondents. In all three health variables, residents in Cluster 4 showed better health outcomes than in the other clusters, as <xref ref-type="table" rid="T2">Table 2</xref> illustrates. For the general subjective health status, only 12.3% of Cluster 4 residents indicated poor general health, while Cluster 3 scored the highest proportion with 25.7%. The differences were not statistically significant, though. Symptoms of impaired mental health were more common than of impaired general health in all clusters. In terms of GAD, more than one in two residents of Cluster 2 indicated symptoms. For Clusters 1 and 3, proportions were also relatively high, with more than 42%. Cluster 4 residents scored lower, around one-third indicated symptoms here. The unadjusted differences in the frequencies of GAD symptoms between the clusters were statistically significant [<italic>x</italic>
<sup>2</sup>
<sub>(df &#x3d; 3)</sub> &#x3d; 13; <italic>p</italic> &#x3d; 0.005]. The proportion of respondents with depression symptoms was lowest in Cluster 4 as well, with approximately 39%. In Clusters 1, 2 and 3, in contrast, around 1 in 2 people indicated symptoms of depression. Differences between the clusters were not statistically significant.</p>
<table-wrap id="T2" position="float">
<label>TABLE 2</label>
<caption>
<p>Health characteristics of respondents grouped by accommodation cluster (Baden-Wuerttemberg, Germany. 2018 [<xref ref-type="bibr" rid="B12">12</xref>])</p>
</caption>
<table>
<thead valign="top">
<tr>
<th rowspan="2" colspan="2" align="left"/>
<th colspan="5" align="center">Cluster</th>
</tr>
<tr>
<th align="center">1</th>
<th align="center">2</th>
<th align="center">3</th>
<th align="center">4</th>
<th align="center">Total</th>
</tr>
</thead>
<tbody valign="top">
<tr>
<td colspan="7" align="left">General subjective health status</td>
</tr>
<tr>
<td rowspan="2" align="left">&#x2003;Poor health</td>
<td align="center">
<italic>n</italic>
</td>
<td align="center">6</td>
<td align="center">38</td>
<td align="center">9</td>
<td align="center">16</td>
<td rowspan="2" align="center">69</td>
</tr>
<tr>
<td align="center">%</td>
<td align="center">16.7</td>
<td align="center">22.5</td>
<td align="center">25.7</td>
<td align="center">12.3</td>
</tr>
<tr>
<td rowspan="2" align="left">&#x2003;Missings</td>
<td align="center">
<italic>n</italic>
</td>
<td align="center">3</td>
<td align="center">21</td>
<td align="center">4</td>
<td align="center">13</td>
<td rowspan="2" align="center">41</td>
</tr>
<tr>
<td align="center">%</td>
<td align="center">7.69</td>
<td align="center">11.05</td>
<td align="center">10.26</td>
<td align="center">9.09</td>
</tr>
<tr>
<td colspan="7" align="left">Generalized Anxiety Disorder (GAD2)</td>
</tr>
<tr>
<td rowspan="2" align="left">&#x2003;GAD symptoms&#x2a;</td>
<td align="center">
<italic>n</italic>
</td>
<td align="center">14</td>
<td align="center">86</td>
<td align="center">18</td>
<td align="center">38</td>
<td rowspan="2" align="center">156</td>
</tr>
<tr>
<td align="center">%</td>
<td align="center">42.4</td>
<td align="center">53.8</td>
<td align="center">48.6</td>
<td align="center">32.2</td>
</tr>
<tr>
<td rowspan="2" align="left">&#x2003;Missings</td>
<td align="center">
<italic>n</italic>
</td>
<td align="center">6</td>
<td align="center">30</td>
<td align="center">2</td>
<td align="center">25</td>
<td rowspan="2" align="center">63</td>
</tr>
<tr>
<td align="center">%</td>
<td align="center">15.38</td>
<td align="center">15.79</td>
<td align="center">5.13</td>
<td align="center">17.48</td>
</tr>
<tr>
<td colspan="7" align="left">Depression (PHQ-2)</td>
</tr>
<tr>
<td rowspan="2" align="left">&#x2003;Depression symptoms</td>
<td align="center">
<italic>n</italic>
</td>
<td align="center">17</td>
<td align="center">79</td>
<td align="center">17</td>
<td align="center">45</td>
<td rowspan="2" align="center">158</td>
</tr>
<tr>
<td align="center">%</td>
<td align="center">51.5</td>
<td align="center">49.1</td>
<td align="center">47.2</td>
<td align="center">38.5</td>
</tr>
<tr>
<td rowspan="2" align="left">&#x2003;Missings</td>
<td align="center">
<italic>n</italic>
</td>
<td align="center">6</td>
<td align="center">29</td>
<td align="center">3</td>
<td align="center">26</td>
<td rowspan="2" align="center">64</td>
</tr>
<tr>
<td align="center">%</td>
<td align="center">15.38</td>
<td align="center">15.26</td>
<td align="center">7.69</td>
<td align="center">18.18</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn>
<p>&#x2a;differences statistically significant (<italic>p</italic> &#x3c; 0.05).</p>
</fn>
</table-wrap-foot>
</table-wrap>
</sec>
<sec id="s3-4">
<title>Results of Regression Analyses</title>
<p>An overview of the results of the regression analyses for poor general health, GAD, and depression (PHQ-2) is provided in <xref ref-type="table" rid="T3">Table 3</xref>. In the age- and gender-adjusted Model 1, Cluster 1, 2 and 3 all showed increased odds for residents having a poor general health status than Cluster 4. Cluster 2 showed the highest odd ratios here and was nearly significant at the 0.05-significance level (OR &#x3d; 2.05; 95%-CI [1.00&#x2013;4.46], <italic>p</italic> &#x3d; 0.058). The adjusted Model 2 showed a significant association of GAD with accommodation type in Cluster 2 (OR &#x3d; 2.7; 95%-CI [1.55&#x2013;4.79], <italic>p</italic> &#x3d; 0.001) and Cluster 3 (OR &#x3d; 2.4; 95%-CI [1.04&#x2013;5.64], <italic>p</italic> &#x3d; 0.042) relative to Cluster 4. In the adjusted model for depression (Model 3), all clusters showed odd ratios larger than 1 relative to Cluster 4 but no association was statistically significant (<italic>p</italic>-values between 0.13 and 0.62).</p>
<table-wrap id="T3" position="float">
<label>TABLE 3</label>
<caption>
<p>Accommodation cluster and health: Logistic regression results (Baden-Wuerttemberg, Germany. 2018 [<xref ref-type="bibr" rid="B12">12</xref>]).</p>
</caption>
<table>
<thead valign="top">
<tr>
<th rowspan="2" align="left"/>
<th colspan="2" align="center">Model 1: General health (<italic>n</italic> &#x3d; 323)</th>
<th colspan="2" align="center">Model 2: GAD (generalized anxiety) (<italic>n</italic> &#x3d; 309)</th>
<th colspan="2" align="center">Model 3: PHQ-2 (Depression) (<italic>n</italic> &#x3d; 308)</th>
</tr>
<tr>
<th align="center">OR (95% CI)</th>
<th align="center">
<italic>p</italic>-value</th>
<th align="center">OR (95% CI)</th>
<th align="center">
<italic>p</italic>-value</th>
<th align="center">OR (95% CI)</th>
<th align="center">
<italic>p</italic>-value</th>
</tr>
</thead>
<tbody valign="top">
<tr>
<td align="left">Constant</td>
<td align="center">0.08&#x2a;&#x2a;&#x2a; (0.03&#x2013;0.23)</td>
<td align="center">0.000</td>
<td align="center">0.37&#x2a; (0.15&#x2013;0.88)</td>
<td align="center">0.026</td>
<td align="center">0.35&#x2a; (0.15&#x2013;0.81)</td>
<td align="center">0.016</td>
</tr>
<tr>
<td align="left">Age</td>
<td align="center">1.01 (0.99&#x2013;1.04)</td>
<td align="center">0.313</td>
<td align="center">1.00 (0.98&#x2013;1.03)</td>
<td align="center">0.783</td>
<td align="center">1.02 (1.00&#x2013;1.04)</td>
<td align="center">0.081</td>
</tr>
<tr>
<td align="left">Gender</td>
<td align="center">1.51 (0.79&#x2013;2.86)</td>
<td align="center">0.204</td>
<td align="center">1.43 (0.85&#x2013;2.42)</td>
<td align="center">0.174</td>
<td align="center">1.07 (0.64&#x2013;1.78)</td>
<td align="center">0.796</td>
</tr>
<tr>
<td align="left">Cluster 1</td>
<td align="center">1.41 (0.41&#x2013;4.28)</td>
<td align="center">0.556</td>
<td align="center">1.25 (0.51&#x2013;2.97)</td>
<td align="center">0.619</td>
<td align="center">1.24 (0.53&#x2013;2.89)</td>
<td align="center">0.620</td>
</tr>
<tr>
<td align="left">Cluster 2</td>
<td align="center">2.05 (1.00&#x2013;4.46)</td>
<td align="center">0.058</td>
<td align="center">2.70&#x2a;&#x2a;&#x2a; (1.55&#x2013;4.79)</td>
<td align="center">0.001</td>
<td align="center">1.52 (0.88&#x2013;2.63)</td>
<td align="center">0.134</td>
</tr>
<tr>
<td align="left">Cluster 3</td>
<td align="center">1.69 (0.54&#x2013;4.89)</td>
<td align="center">0.343</td>
<td align="center">2.40&#x2a; (1.04&#x2013;5.64)</td>
<td align="center">0.042</td>
<td align="center">1.28 (0.55&#x2013;2.96)</td>
<td align="center">0.558</td>
</tr>
<tr>
<td align="left">Nagelkerke <italic>R</italic>
<sup>2</sup>
</td>
<td colspan="2" align="center">0.035</td>
<td colspan="2" align="center">0.069&#x2a;</td>
<td colspan="2" align="center">0.025</td>
</tr>
<tr>
<td align="left">AIC (Akaike Information Criterion)</td>
<td colspan="2" align="center">275.9</td>
<td colspan="2" align="center">387.2</td>
<td colspan="2" align="center">397.4</td>
</tr>
</tbody>
</table>
<table>
<thead valign="top">
<tr>
<th rowspan="2" align="center"/>
<th colspan="2" align="center">Model 4: GAD &#x2b; PHQ-2 &#x3d; 1 (<italic>n</italic> &#x3d; 302)</th>
<th colspan="2" align="center">Model 5: GAD &#x2b; PHQ-2 &#x3d; 0 (<italic>n</italic> &#x3d; 302)</th>
<th colspan="2" align="center">Model 6: GAD OR PHQ-2 &#x3d; 1 (<italic>n</italic> &#x3d; 302)</th>
</tr>
<tr>
<th align="center">OR (95% CI)</th>
<th align="center">
<italic>p</italic>-value</th>
<th align="center">OR (95% CI)</th>
<th align="center">
<italic>p</italic>-value</th>
<th align="center">OR (95% CI)</th>
<th align="center">
<italic>p</italic>-value</th>
</tr>
</thead>
<tbody valign="top">
<tr>
<td align="left">Constant</td>
<td align="center">0.15&#x2a;&#x2a;&#x2a; (0.06&#x2013;0.37)</td>
<td align="center">0.000</td>
<td align="center">1.31 (0.56&#x2013;3.13)</td>
<td align="center">0.530</td>
<td align="center">0.64 (0.15&#x2013;0.81)</td>
<td align="center">0.380</td>
</tr>
<tr>
<td align="left">Age</td>
<td align="center">1.02 (1.00&#x2013;1.04)</td>
<td align="center">0.098</td>
<td align="center">1.00 (0.97&#x2013;1.02)</td>
<td align="center">0.650</td>
<td align="center">0.98 (1.00&#x2013;1.04)</td>
<td align="center">0.180</td>
</tr>
<tr>
<td align="left">Gender</td>
<td align="center">1.44 (0.84&#x2013;2.47)</td>
<td align="center">0.188</td>
<td align="center">0.91 (0.54&#x2013;1.52)</td>
<td align="center">0.712</td>
<td align="center">0.73 (0.64&#x2013;1.78)</td>
<td align="center">0.320</td>
</tr>
<tr>
<td align="left">Cluster 1</td>
<td align="center">0.99 (0.35&#x2013;2.57)</td>
<td align="center">0.988</td>
<td align="center">0.66 (0.29&#x2013;1.53)</td>
<td align="center">0.334</td>
<td align="center">1.68 (0.53&#x2013;2.89)</td>
<td align="center">0.260</td>
</tr>
<tr>
<td align="left">Cluster 2</td>
<td align="center">2.23&#x2a;&#x2a; (1.24&#x2013;4.10)</td>
<td align="center">0.009</td>
<td align="center">0.50&#x2a; (0.29&#x2013;0.86)</td>
<td align="center">0.013</td>
<td align="center">0.99 (0.88&#x2013;2.63)</td>
<td align="center">0.970</td>
</tr>
<tr>
<td align="left">Cluster 3</td>
<td align="center">2.01 (0.85&#x2013;4.95)</td>
<td align="center">0.107</td>
<td align="center">0.62 (0.27&#x2013;1.43)</td>
<td align="center">0.270</td>
<td align="center">0.80 (0.55&#x2013;2.96)</td>
<td align="center">0.670</td>
</tr>
<tr>
<td align="left">Nagelkerke <italic>R</italic>
<sup>2</sup>
</td>
<td colspan="2" align="center">0.062&#x2a;</td>
<td colspan="2" align="center">0.031</td>
<td colspan="2" align="center">0.026</td>
</tr>
<tr>
<td align="left">AIC</td>
<td colspan="2" align="center">360.3</td>
<td colspan="2" align="center">390</td>
<td colspan="2" align="center">323.6</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn>
<p>Notes: Reference categories: male, cluster 4. Significant at &#x2a;5, &#x2a;&#x2a; 1 and &#x2a;&#x2a;&#x2a; 0.1 percent levels, respectively (for overall models, likelihood ratio tests (LRT) were used).</p>
</fn>
</table-wrap-foot>
</table-wrap>
</sec>
<sec id="s3-5">
<title>Distribution of Depression and Generalized Anxiety Disorder in the Clusters</title>
<p>In the sample, depression and anxiety disorders were correlated (<italic>r</italic> &#x3d; 0.52). We additionally assessed the distribution of depression and GAD in the clusters (see <xref ref-type="fig" rid="F1">Figure 1</xref>) and analysed how regression results changed when using these distribution variables as dependent variables (see <xref ref-type="table" rid="T3">Table 3</xref>). Higher proportions of residents in all clusters showed both symptoms than GAD symptoms without depression, or <italic>vice versa</italic> Only cluster differences found for both symptoms present were statistically significant [<italic>x</italic>
<sup>2</sup>
<sub>(df &#x3d; 3)</sub> &#x3d; 8; <italic>p</italic> &#x3d; 0.05].</p>
<fig id="F1" position="float">
<label>FIGURE 1</label>
<caption>
<p>Distribution of depression (PHQ-2) and generalized anxiety disorder (GAD) symptoms in the total sample and grouped by refugee accommodation cluster (Baden-Wuerttemberg, Germany. 2018 [<xref ref-type="bibr" rid="B12">12</xref>]).</p>
</caption>
<graphic xlink:href="ijph-68-1605786-g001.tif"/>
</fig>
<p>In the regression analyses, we found age- and gender-adjusted significant differences between Cluster 2 and 4 (OR &#x3d; 2.3; 95%-CI [1.24&#x2013;4.10]; <italic>p</italic> &#x3d; 0.009) in the model for comorbid GAD and depression (Model 4, <xref ref-type="table" rid="T3">Table 3</xref>). A model for the absence of both conditions (Model 5) supported these results, again indicating significant effects for Cluster 2. Further, a model for the presence of either GAD or depression symptoms could not identify any statistically significant cluster effects.</p>
</sec>
</sec>
<sec sec-type="discussion" id="s4">
<title>Discussion</title>
<p>Collective refugee accommodation centres are considered to be postmigration stress factors impacting health [<xref ref-type="bibr" rid="B18">18</xref>]. However, to the best of our knowledge, empirical research investigating health impacts of collective accommodation has put little emphasis on contextual differences in the accommodation setting as such.</p>
<p>In Germany, collective accommodation is subject to substantial variability regarding size, location, and the quality of the housing environment. We aimed to devise a typology of refugee accommodation by conducting a cluster analysis and to analyse associations between different accommodation types and health. We identified four accommodation clusters: 1) a large accommodation type, located in central urban areas with visible deteriorated housing conditions (mean total SHED &#x3d; 3.6/6); 2) a large-to-medium sized accommodation type frequently located in rural areas (though still located close to amenities) with few deteriorated conditions (mean total SHED &#x3d; 1.1/6); 3) a small accommodation type, predominantly located in urban areas with negligible levels of housing deterioration (mean total SHED &#x3d; 0.8/6) but remotely located from important amenities; and 4) a small to medium sized accommodation type located partially in rural areas but close to amenities and with negligible levels of housing deterioration (mean total SHED &#x3d; 0.8/6).</p>
<p>Our analyses consistently show that the best health outcomes could be found where residents lived in less crowded, less deteriorated, and less remotely located accommodation centres. There, residents suffer less frequently from GAD and depression, and more often report to be in good general health. In subsequent analyses, we also found that overall, a high proportion of residents showed comorbid symptoms of GAD and depression, odds for unfavourable health outcomes being significantly higher in Cluster 2 compared to Cluster 4. This is consistent with other findings pointing to comorbidity of depression and anxiety disorder [<xref ref-type="bibr" rid="B19">19</xref>&#x2013;<xref ref-type="bibr" rid="B21">21</xref>].</p>
<p>Assuming the contextual differences in Cluster 2 and 3 compared to Cluster 4 are associated with the health outcomes in the clusters, issues of crowded dwellings, housing deterioration but also remoteness should be investigated more closely. Studies assessing the health impact of housing among refugee and asylum seeker populations in resettlement countries frequently point to issues of overcrowding, especially when the accommodation must be shared with strangers and health needs vary between the residents [<xref ref-type="bibr" rid="B22">22</xref>]. Evans et al. [<xref ref-type="bibr" rid="B23">23</xref>] found a consistent positive relationship between overcrowding (measured by number of rooms per people) and psychological distress in different institutionalized populations (e.g., among prisoners or college students). The authors also pointed to indirect pathways linking the built environment to mental problems. More crowded residential settings can lead to social withdrawal with negative consequences for the development and maintenance of socially supportive relationships.</p>
<p>Research investigating health impacts of the physical environment of refugee accommodation is yet sparse, but our findings are supported by evidence from the literature assessing neighbourhood disorder. A meta-analysis by O&#x2019;Brien et al. [<xref ref-type="bibr" rid="B24">24</xref>] found a persistent association of neighbourhood disorder with unfavourable mental health outcomes as well as overall health. The results support the psychosocial model of disadvantage, indicating that stressful conditions&#x2014;such as deteriorated neighbourhoods&#x2014;can affect mental health, though the studies assessed were mainly cross-sectional, thus not allowing to confirm causality. We also found that among the different aspects of housing deterioration, garbage accumulation showed a strong effect. More research on this association is needed [<xref ref-type="bibr" rid="B25">25</xref>].</p>
<p>We did not find consistent evidence whether and how remoteness, i.e., the distance to important amenities, is associated with health. While an association between urban environment and poorer mental health outcomes is well documented, there is low evidence that remoteness is associated with mental illness. Peen et al. [<xref ref-type="bibr" rid="B26">26</xref>] argued that a range of stress factors potentially harmful for mental health are more prevalent in urban areas than in rural areas, i.e., social factors such as life events and social isolation, or physical factors such as crowded housing, high population density, and air pollution. Adli and Sch&#xf6;ndorf [<xref ref-type="bibr" rid="B27">27</xref>] support the assumption that urban districts induce social stress which in turn can increase the risk of mental illness. While Eckert et al. [<xref ref-type="bibr" rid="B28">28</xref>] and Goldney et al. [<xref ref-type="bibr" rid="B29">29</xref>] found no associations between remoteness and mental illness in Australia, Kelly et al. [<xref ref-type="bibr" rid="B30">30</xref>] found higher risk of mental problems for residents living in more remote areas. In all three studies, remoteness was defined by road distance to services. Kelly et al. [<xref ref-type="bibr" rid="B30">30</xref>] pointed to the geographic variabilities in mental health but also raised the question whether the observed association may be less due to the remoteness itself but rather due to associated regional characteristics such as social isolation, community size, or socioeconomic position.</p>
<sec id="s4-1">
<title>Strengths and Limitations</title>
<p>We have addressed contextual variabilities of collective refugee accommodation centres in Germany to investigate associations between housing and refugee health in a comparative way. By using a cluster analysis approach, we identified four distinct types of refugee accommodation. This enabled us to go beyond regular multivariate analyses based on individual contextual characteristics and focus on contextual combination of different characteristics when assessing their associations with health and presenting health disparities.</p>
<p>Cluster size varied considerably, ranging from 39 cases to 190 respondents. Since one of the smaller clusters was consistent and repeatedly occurred in different pre-analyses with varying clustering approaches, we decided to accept the variability in cluster size (and the small number of accommodation centres cluster 1 was based on), being aware that the clusters can be compared with each other only to a limited extent.</p>
<p>In regression analyses, only few effects were found to be statistically significant. This may be due to the small sample sizes in some of the clusters. Especially Cluster 1 failed to yield significant associations relative to Cluster 4. Another statistical issue was missing values in the data for GAD and depression. Whereas the percentages of missings were relatively even in Cluster 1, 2 and 4, Cluster 3 had lower rates of missings (see <xref ref-type="table" rid="T2">Table 2</xref>). Since Cluster 4 contained the highest number of missings overall with 17.5% (GAD) and 18.3% (depression), associations found in this analysis could have been weaker and frequencies of residents showing GAD and depression symptoms could have been higher. By using PHQ2, we may have underestimated negative mental health effects besides depression. Future studies should further explore the concept of &#x201c;demoralization&#x201d; [<xref ref-type="bibr" rid="B31">31</xref>] among asylum seekers and refugees, especially given its relevance for suicidal ideation and behavior [<xref ref-type="bibr" rid="B32">32</xref>].</p>
<p>Further, we could identify few cluster differences regarding urbanity. Given our definition of urbanity, it is rather unsurprising that each accommodation type identified here was predominantly located in urban districts. For example, in Baden W&#xfc;rttemberg, where data has been collected, overall population density was 311 inhabitants per km<sup>2</sup> in 2019 [<xref ref-type="bibr" rid="B33">33</xref>], far above the cut-off applied here. However, as refugees are distributed to districts according (among other factors) their population size, the majority of refugees will be accommodated in more urban areas.</p>
<p>Also, we could not investigate to which extent the residents of the larger accommodation types lived in overcrowded settings according to the Eurostat definition since the data did not provide information about room numbers of the accommodation centres assessed. However, with an average number of residents of up to 150, we can assume that the specifications of the Eurostat definition are not met, and that residents of these accommodations (clusters 1 and 2) share rooms. As the Eurostat definition applies to private households rather than to collective accommodation centres, a more appropriate concept should be developed.</p>
<p>Additionally, given the important role of work and workplace in potentially shaping health as well as facilitating societal and language integration, future analyses could be enriched by data on transient employment and workplace distance. At the same time, an overall such effect may be subsumed under our data on remoteness in terms of distance to shops, medical or administrative services.</p>
<p>The cross-sectional design of the data allowed us to identify only associations between the accommodation cluster and unfavourable health outcomes. Longitudinal approaches are needed to assess whether the accommodation types are causally associated with certain health outcomes. O&#x2019;Brien et al. [<xref ref-type="bibr" rid="B24">24</xref>] for example argued that poor mental health may also result in more negative assessments of the physical environment. Since the SHED index was assessed by researchers, not by residents themselves, this form of same-source bias is unlikely here. It may be possible, though, that researchers would consider the accommodation as run-down while refugees might appreciate the conditions compared to other accommodation settings they have experienced during flight.</p>
<p>Future research should also account for the stage of the asylum application process of interviewees. For example, it is possible that Cluster 4 contained a lower proportion of residents whose asylum claim was still under process, which has been found to be a significant predictor of mental health problems [<xref ref-type="bibr" rid="B34">34</xref>]. Since asylum seekers live more often in deprived areas with unfavourable living conditions [<xref ref-type="bibr" rid="B35">35</xref>] like a run-down physical environment, the pathway of how exactly accommodation type impacts health warrants further research.</p>
</sec>
<sec id="s4-2">
<title>Conclusion</title>
<p>The context in which people live can affect their health in many ways. By conducting a cluster analysis of variables related to refugee accommodation in Germany, we have identified four different accommodation types reflecting contextual differences in the number of inhabitants, the degree of housing deterioration, and the distance to important amenities, thereby contributing to the development of a typology of refugee accommodation. The accommodation type with a moderate number of occupants, lowest levels of deterioration, and a central and urban location was associated with favourable health outcomes in terms of subjective general health status, depression, and GAD&#x2014;the latter most strongly. The odds of unfavourable health increased for accommodation clusters that either showed a high state of decay and a large accommodation size (Cluster 2), or a small accommodation size remote from important amenities (Cluster 3). Effects were weakest for depression. Subsequent analyses showed, though, that when assessing comorbidity of GAD and depression, the larger, more deteriorated accommodation type (Cluster 2) yielded similar significant effects compared to the analysis of GAD alone. The findings from this study should be considered in political decisions on the layout as well as the choice of location of collective accommodation centres in Germany and comparable countries.</p>
</sec>
</sec>
</body>
<back>
<sec sec-type="data-availability" id="s5">
<title>Data Availability Statement</title>
<p>Data are available from the authors upon reasonable request.</p>
</sec>
<sec id="s6">
<title>Ethics Statement</title>
<p>The studies involving humans were approved by ethics committee of the Medical Faculty of Heidelberg on 12 October 2017 (S- 516/2017). The studies were conducted in accordance with the local legislation and institutional requirements. The participants provided their written informed consent to participate in this study.</p>
</sec>
<sec id="s7">
<title>Author Contributions</title>
<p>AM: Study conceptualisation, data collection, data management, writing of final version. VD: Study conceptualisation, methodology, data analysis, writing of original draft. KB: Project and study conceptualisation, funding acquisition, project management, data collection, draft revision. LB: Project and study conceptualisation, project management, data collection, data management, draft revision. OR: Study conceptualisation, methodology, draft revision. OS: Study conceptualisation, methodology, draft revision. All authors contributed to the article and approved the submitted version.</p>
</sec>
<sec id="s8">
<title>Funding</title>
<p>The primary data collection was funded by the German Federal Ministry for Education and Research (BMBF) in the scope of the project RESPOND (Grant Number: 01GY1611). The study was realised with funding of the German Science Foundation (DFG) in the scope of the Research Unit PH-LENS (FOR 2928), subprojects DEPRIV (409654512) and NEXUS (GZ: BO 5233/1-1). AM acknowledges financial support by the Else Kr&#x00F6;ner-Fresenius-Stiftung (2017_Promotionskolleg.08) within the Heidelberg Graduate School of Global Health. The funders had no influence on study design, analysis, or decision to publish. We acknowledge the financial support of the Open Access Publication Fund of Bielefeld University for the article processing charge.</p>
</sec>
<sec sec-type="COI-statement" id="s9">
<title>Conflict of Interest</title>
<p>The authors declare that they do not have any conflicts of interest.</p>
</sec>
<ack>
<p>We thank all study participants for their time and trust. Furthermore, we thank the editor and the reviewers for their valuable contributions to the manuscript. An earlier version of this manuscript has been uploaded to a preprint server, medRxiv, ahead of submission to this journal [<xref ref-type="bibr" rid="B36">36</xref>].</p>
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