Medical aid in dying (MAID) has emerged as one of the most complex and emotionally charged topics in healthcare [1–4]. While proponents argue that it offers a compassionate option for those facing unbearable suffering, critics raise concerns about the possibility for abuse and how this might impact society’s most vulnerable members. To truly understand the implications of MAID, we must not only follow the journey of that the person requesting MAID but also that of the others involved: patients, families, healthcare providers, and society at large. In this special issue, several themes and perspectives regarding MAID are highlighted from different countries (see Table 1).

Starting at the center of MAID’s focus, there are the individuals who seek this option. Research by Currin-McCulloch et al. (United States) provide valuable insights into the decision-making processes of these patients. Their study reveals that the motivation for a patient to request MAID is far from simple or straightforward. It is a highly personal decision-making process that rests against personal experiences that are greatly impacted by societal controversy and social pressure in the United States. This context, potentially adding to the tensions intrinsic to the process of seeking MAID, underscores the need for robust support and care systems with clear communication between patients, families, and healthcare professionals.

The support needs of patients and their relatives throughout MAID trajectories is addressed by Vissers et al. (Belgium). Their qualitative study identified eight categories of assistance needs, from facilitating social interaction and handling organizational and practical issues to support for relatives to understand the patient’s desire for MAID. As the authors conclude that patients and relatives experience the MAID trajectory as social and existential rather than only medical, patients requesting MAID and their relatives may benefit from a palliative care approach, just like patients and their relatives in other end-of-life trajectories. An integrated approach of MAID and palliative care seems warranted, rather than viewing them as conflicting paths for end-of-life care.

The importance of family dynamics and support networks in MAID trajectories is also reflected in a study by Sperling (Israel) on family members and close friends that support patients who travel to Switzerland for MAID. This study highlights the complex emotional landscape navigated by loved ones during this process. Families often struggle with supporting and facilitating the patient’s request, the impact of traveling to another country with entirely different surroundings, and handling procedures after the patient’s death. These findings show several unfulfilled support needs of families and other loved ones that are also present in the study by Vissers et al., but in the case of “suicide tourism” these inadequacies are even more obvious.

As some of the countries with MAID legislation do not require patients to have a lethal disease to be eligible for MAID, special considerations arise regarding MAID requests from patients with age-related health problems. Kraak-Steenken et al. (The Netherlands) found that people with an accumulation of health problems related to old age that requested assisted dying most often had osteoarthritis, vision and/or hearing impairment. Their primary reasons for requesting assisted dying included physical decline, dependency, general weakness/fatigue and (fear of) losing control of one’s life. The researchers also found that patients with certain characteristics, e.g., care dependence, disability/immobility, loss of control and a treatment relationship with the physician longer than a year, were more likely to have their request granted. In contrast, having “no purpose in life” or “not wanting to be a burden” lowered the likelihood of a granted request for MAID. These findings raise challenging questions about the nature of suffering, the role of family and society and how physicians deal with individuals handle those wishing to die due to an accumulation of age-related conditions. Greater understanding of these topics can contribute to the ongoing debate on the acceptability of MAID for people without life-threatening conditions.

MAID requests in countries with MAID legislation also place significant demands on healthcare professionals navigating the patient’s journey. Research by Perron et al. (Canada) underscores the legal, administrative, clinical, emotional and ethical challenges faced by physicians and other healthcare professionals involved in MAID, especially in countries with increasing counts of MAID requests. They examined interdisciplinary support groups for professionals involved in MAID in Quebec, and found that they vary significantly. The working practices of the organizations ranged from acting as a central point of contact that is entirely responsible throughout end-of-life procedures, to providing support only. A “middle ground” between these two positions was preferred, in which the MAID trajectory is the doctor’s responsibility but support is provided by a team. Although support groups like these require adaptation to the specific reality of every context, this study provides valuable insights for the development of support structures for healthcare providers involved in MAID.

One often overlooked aspect of the MAID journey is the need for comprehensive aftercare for bereaved relatives and healthcare workers. Renckens et al. (Netherlands) shed light on current practices in such provisions following euthanasia or physician-assisted suicide. Aftercare focused on practical aspects of the MAID journey, the emotional experience of relatives during the MAID trajectory, and relatives' current mental wellbeing. Their findings also reveal significant gaps in support for these families post-MAID. The authors conclude that aftercare conversations with a physician covering a wide-range of topics are likely to be valuable for all bereaved relatives, and not just for “at risk” populations typically targeted by policies and guidelines.

In conclusion, in the light of the different MAID legislation, policies and practices around the world, the presented studies provide a small snapshot of a very complex and important aspect of healthcare. As we look to the future of MAID, it is clear that a holistic and interdisciplinary approach is needed to support not only the person seeking to enter this journey but also family, friends and healthcare professionals. This complex issue touches on medicine, ethics, law, psychology, and sociology, among other disciplines. Future research should focus on expanding our understanding of the diverse practices, contexts, and implications related to end-of-life care for those wishing to die, families, the bereaved, physicians, and other healthcare professionals. It is crucial to gain deeper insights into current practices and legislation, allowing for critical analysis and identification of areas for improvement. This research should adopt an international perspective and consider cultural aspects to develop a more comprehensive understanding of the field.