AUTHOR=Nunes Ana Beatriz , Teixeira José Pedro , Leite Andreia , Schäfer Willemijn , Valli Claudia , Martínez-Nicolas Ismael , Paixão Margarida , Seyfulayeva Ayshe , Abelenda Daniel Treviño , Rodríguez Anna , Carvalho Pedro Casaca , Heideveld-Chevalking Anita , Emond Yvette , Põlluste Kaja , Calsbeek Hiske , Arnal-Velasco Daniel , Žaludek Adam , Garel Pascal , Wagner Cordula , Groene Oliver , Orrego Carola , Sousa Paulo , SAFEST Scientific Advisory Group , SAFEST Scientific Executive Group , SAFEST Consortium TITLE=Core Measure Set for Patient Safety in Perioperative Care: A Clinical Practice-Oriented Consensus Study JOURNAL=International Journal of Public Health VOLUME=Volume 71 - 2026 YEAR=2026 URL=https://www.ssph-journal.org/journals/international-journal-of-public-health/articles/10.3389/ijph.2026.1609159 DOI=10.3389/ijph.2026.1609159 ISSN=1661-8564 ABSTRACT=ObjectivesTo develop a consensus-based EU-wide Core Measure Set (CMS), including patient-reported measures, for evaluating perioperative patient safety in routine adult care.MethodsA four-phase approach was applied: 1) identification of candidate structure, process, and outcome measures through three literature reviews; 2) synthesis into an initial list via deduplication and merging; 3) consensus process using a two-round modified eDelphi technique, with subject-matter and lived-experienced experts rating the importance and feasibility of each measure (consensus: ≥75% rating 7–9, ≤15% rating 1–3), followed by an online Consensus Conference addressing measures highly valued by patients but lacking feasibility consensus; 4) refinement of the CMS for patient safety in perioperative care (CMS-PSPC).ResultsOut of 9,717 records identified, 340 studies were included, yielding 1,305 measures. After refinement, 247 measures were consolidated; 84 reached consensus, and ten more were added via the Consensus Conference. The final CMS-PSPC comprised 76 measures: 22 outcome, 18 process, and 36 structure measures.ConclusionThe CMS-PSPC provides a standardised, patient-centred framework for evaluating, monitoring and benchmarking perioperative patient safety in routine clinical care, supporting EU-wide quality improvement efforts.