AUTHOR=Muxunov Alimzhan , Kalinina Dina , Okpechi Ikechi , Lowe-Jones Racquel , Gaipov Abduzhappar , Kuanshaliyeva Zhanat , Bayakhmetova Symbat , Madikenova Meruyert , Sarria-Santamera Antonio 
  
TITLE=Key determinants of self-management in patients with non-dialysis-dependent chronic kidney disease: a systematic review
  
JOURNAL=Public Health Reviews
  
VOLUME=Volume 47 - 2026
  
YEAR=2026
  
URL=https://www.ssph-journal.org/journals/public-health-reviews/articles/10.3389/phrs.2026.1609108
  
DOI=10.3389/phrs.2026.1609108
  
ISSN=2107-6952
  
ABSTRACT=ObjectivesAdoption of recommended self-management behaviors has been associated with a lower risk of disease progression, cardiovascular morbidity, and mortality in patients with chronic kidney disease (CKD). This systematic review aims to identify factors associated with the adherence of non-dialysis-dependent CKD (NDD-CKD) patients to recommended self-management practices.MethodsFollowing PRISMA guidelines, we searched PubMed, Embase, Scopus, Medline, and CINAHL Plus databases from 1st January 2010 to 30th June 2024. The extracted data included associations of variables with self-management scores. The findings were descriptively presented in a grouped tabular form. The study was registered with the PROSPERO, CRD42024547304.ResultsFrom 1,914 studies identified, 16 cross-sectional studies with 3,658 participants were selected for inclusion. Objective CKD knowledge, health literacy, self-efficacy and social support consistently showed positive associations with self-management across multiple studies.ConclusionThis systematic review revealed multiple factors associated with self-management in NDD-CKD patients, with disease-related knowledge, health literacy, and self-efficacy showing the most consistent positive associations across studies. Healthcare providers and policymakers should develop and implement health literacy and awareness programs as a strategy for improving patient outcomes.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?RecordID=547304, identifier CRD42024547304.